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병원소개
찾아오시는길
분당서울대학교병원에 찾아오시는 길입니다.
우)13620, 경기도 성남시 분당구 구미로173번길 82
대중교통 이용-
- 미금역에서 버스 이용시
- 미금역 3번 출구 → 마을버스(7번, 7-1번), 8446번 버스 탑승 → 분당서울대학교병원
- 미금역 2번 출구 → 51번 버스 탑승 → 분당서울대학교병원
- 미금역 8번 출구 → 마을버스(19번), 380번 버스 탑승 → 분당서울대학교병원
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- 오리역에서 버스 이용시
- 오리역 7번 출구 → 10m 앞 마을버스(19번) 탑승 → 분당서울대학교병원
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- 정자역에서 버스 이용시
- 정자역 3번 출구 → 마을버스(19번, 111번), 380번, 8446번 버스 탑승 → 분당서울대학교병원
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- 헬스케어혁신파크(상행) 하차시
- 분당서울대학교병원 방향 탄천길로 도보 15분
자동차 이용-
- 판교 IC 방면
- 판교 IC → 분당방향으로 직진 → 서현로 → 분당구청 방향으로 우회전 → 분당구청 → 분당정보산업고교에서 좌회전 → 돌마교사거리에서 직진 → 아름다운 교회에서 좌회전 → 미금교 → 분당서울대학교병원
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- 성수대교 방면
- 성수대교 → 구룡터널 → 분당내곡간 고속화도로(약 15분 직진) → 분당 도착해서 직진 → 분당구청 → 수내역 방향으로 우회전 → 정자역 → 분당정보산업고교에서 좌회전 → 돌마교사거리에서 직진 → 아름다운 교회에서 좌회전 → 미금교 → 분당서울대학교병원
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- 청담대교 방면
- 청담대교 → 분당수서간 고속화도로(약 25분 직진) → 초림지하차도 → 정자지하차도(2번째 지하도) 지난 후 우측차선으로 빠짐 → 미금역 방향 → 미금역 방향으로 좌회전 → 돌마교사거리에서 우회전 → 700m정도 직진 → 아름다운 교회에서 좌회전 → 미금교 → 분당서울대학교병원
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- 수원 IC 방면
- 수원 IC → 신갈오거리 → 신갈중학교 앞 → 구성삼거리 → 마북삼거리 → 보정교차로 → 죽전사거리 → 오리역 → 낙생교 지나자마자 우회전 → 미금교 → 분당서울대학교병원
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- 수서역 SRT 방면
- 밤고개로(약 5분 직진) → 분당내곡간 고속화도로(약 10분 직진) → 분당 도착해서 직진 → 분당구청 → 수내역 방향으로 우회전 → 정자역 → 분당정보산업고교에서 좌회전 → 돌마교사거리에서 직진 → 아름다운 교회에서 좌회전 → 미금교 → 분당서울대학교병원
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공지사항
공지사항
분당서울대학교병원의 공지사항을 알려드립니다.
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건강정보
건강정보
다양하고 유익한 건강상식을 제공해 드립니다.
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- 40만 개의 난포로 생명 탄생을 이끄는 난소 바로알기!
- 여성의 몸은 생명을 잉태하기 위한 신비한 신체 기관을 갖추고 있다. 이런 여성 생식기관 중 중요한 역할을 담당하는 것이 바로 자궁과 난소다. 자궁은 길이 약 8~9㎝, 폭 6㎝, 두께 4㎝, 무게 50㎎ 정도의 작은 기관이다. 하지만 임신 후에는 20배가량 늘어나며, 용적도 임신 전보다 500배로 커진다. 이런 자궁 뒤쪽으로는 2개의 난소가 좌우에 각각 1개씩 자리 잡고 있다. 난자를 보관하고 배란하는 난소 난소는 작은 살구나 아몬드 모양의 타원형 구조를 띤다. 신생아나 소아기에는 작고 긴 모양이다가 사춘기에 이르러 점 차 커지고, 폐경 후에는 다시 작아진다. 좌우 나팔관 아랫부분에 1개씩 존재한다. 난소는 피질(겉)과 수질(속)로 구성된 다. 피질은 다양한 크기의 난포(여포)를 포함하고 수질은 섬유근육 조직과 혈관으로 되어있다. 난포는 주머니 모양의 세 포 집합체로 난자를 포함하고 있으며 난자의 배란 후 황체로 변화한다. 난소의 크기는 다양하지만, 정상 난소의 경우 일 반적으로 길이 약 3~5㎝, 무게 7~10g 정도에 해당한다. 표면은 난소간막이라는 복막에 둘러싸여 있다. 여성은 보통 미성숙 난자인 원시난포를 200만 개가량 가지고 태어난다. 이중 약 40만 개 정도가 사춘기까지 생존해 난 포로 자라난다. 월경주기마다 여러 개의 난포가 함께 동원되지만 최종적으로 한 개의 난포만 성숙하여 배란된다. 폐경 기를 맞아 생식능력을 잃으면 남아 있던 난포도 모두 퇴화하므로, 여성은 평생의 가임기간 동안 400여 개의 난포만을 성숙시키는 셈이다. 난소는 난자를 만들고 보관하며 성숙시켜 배란(방출)이 이루어지도록 하는 기관이다. 이때 배란된 난자는 나팔관을 통 해 자궁으로 이동한다. 난소의 또 다른 기능은 호르몬 생성이다. 에스트로겐, 프로게스테론 같은 여성 호르몬과 소량의 테스토스테론 같은 남성 호르몬을 분비한다. 이들 호르몬의 분비는 시상하부, 뇌하수체에서 분비되는 자극 호르몬들과 상호작용을 통해 조절된다. 난소의 기능은 경구피임약, 생식샘자극호르몬방출 호르몬 유사체(Gonadotropin Releasing Hormone (GnRH) Analogue), 배란 유도제, 항암 치료 등의 약제, 스트레스, 영양상태 등 외부의 영향에 따라 변화할 수 있다. 난소의 크기 도 이에 영향을 받을 수 있다. 난소 건강에 대한 궁금증 풀이 ➊ 난소 나이는 신체 나이와일치하지 않는다? 요즘에는 항뮬러관 호르몬(Anti-Müllerian Hormone, AMH) 검사를 통해 간단한 채혈 만으로 ‘난소 나이’를 측정할 수 있다. 월경주 기에 상관없이 검사할 수 있다. 미성숙 난포에 서 분비되는 호르몬 수치가 높으면 난소 안에 배란될 난포들이 많다는 뜻이며, 그 수치가 낮 으면 배란될 난포가 적다고 볼 수 있다. 난소 의 나이는 신체 나이와 꼭 일치하지 않는다. 같은 연령대의 여성이라도 AMH 수치가 다르 고 원시난포의 경우는 100배까지 차이 나는 경우도 있다. ➋ 난소 건강이 안 좋을 때전조증상이 있다? 난소 기능 저하를 미리 가늠할 수 있는 증상 은 없다. 대부분 월경주기 및 양에 변화가 생 겨 병원을 찾았다가 우연히 난소 기능의 저하 를 발견하곤 한다. 아예 아무런 특이 증상이 없는 환자도 많다. 따라서 임신을 계획하고 있 는 여성이라면, 난소 기능 검사를 통해 본인의 상태를 정확히 파악해 보는 것이 좋다. ➌ 난자 냉동이 필요할까? 최근 들어 난자를 냉동하는 이들이 늘고 있다. 난소 질환이 있는 경우, 난소 기능이 저하된 경우, 아직 미혼으로 당장 결혼 및 출산 계획 이 없는 경우 등은 난자 냉동을 고려해 볼 수 있다. 단, 나이가 많아도 자연임신이 가능하 고, 시술로도 임신이 가능하므로 반드시 먼저 산부인과 전문의와 상담해야 한다 난소 관련 질환은? ‘난소낭종(Ovarian Cyst, Ovarian Cystic Tumor)’은 난소에 발생하는 종양으로, 기능성(생리적) 낭종과 양성 난소 종양 (혹)을 통칭하는 개념이다. 대개 크지 않고 양성이며 암이 아닌 경우가 대부분이다. 기능성 낭종은 흔히 물혹이라고도 불리는데 내부가 액상 성분으로 차 있기 때문이다. 기능성 낭종은 청소년기와 가임기 연령의 배란 과정에서 흔히 발생 할 수 있다. 8㎝를 초과하는 경우는 드물며 보통 수주에서 수개월 사이에 저절로 없어진다. 하복부 통증, 요통, 잦은 소 변, 복부 팽만감, 배변 장애 등이 나타날 수 있으나 낭종이 꼬일 경우엔 심한 복통이 동반되기도 한다. 하지만 무증상인 경우가 대부분이라 골반 진찰 시 만져지거나 골반 초음파 검사 시 확인 되는 경우가 많다. 필요에 따라 CT나 MRI 등 추 가 검사를 시행할 수 있다. 기능성 낭종이라도 종류에 따라 배란이나 임신에 영향을 주어 불규칙한 생리나 난임을 초래 할 수 있다. 난소낭종이 자연적으로 사라지지 않고 지속해 관찰될 경우는 치료가 필요하다. 치료는 증상의 유무와 환자의 연령, 종 양의 크기, 악성 가능성 등 여러 요소를 고려해 판단하게 된다. 젊은 연령층에서 발생하는 작은 기능성 낭종은 주기적인 관찰만으로도 충분하다. 종양이 갑자기 커지거나 악성이 의심되는 경우는 수술을 통해 제거해야 한다. 특히 폐경기가 지난 여성, 가족이나 본인이 유방암 또는 자궁내막암, 난소암 등을 앓았던 경험이 있거나 종괴가 점점 커지는 경우엔 적 극적으로 수술을 고려해야 한다. ‘다낭난소증후군(Polycystic Ovary Syndrome)’’은 난소에서 배란이 잘 이뤄지지 않아 발생한다. 월경 불순과 난임이 유 발될 수 있고 이외에 다모증, 여드름 등이 동반될 수 있다. 장기적으로는 대사증후군과도 연관된다. 가임기 여성에게서 흔하게 나타나며 유병률은 6~15% 정도다. 아직 명확한 발병 원인이 밝혀지지 않았으나 시상하부-뇌하수체-난소의 호 르몬 불균형, 인슐린 저항성, 남성 호르몬 과다분비 등 여러 가지 요인이 제시되고 있다. 다낭난소증후군 환자는 난소에서 여성 호르몬인 에스트로겐은 정상 분비되지만, 배란이 되지 않아 황체호르몬이 생성 되지 않는다. 황체호르몬은 자궁 내막이 과도하게 증식하는 것을 막아주는데, 다낭난소증후군 환자는 이 황체호르몬이 생성되지 않으므로 자궁 내막이 과도하게 증식하고 자궁내막암 발생도 증가한다. 실제로 다낭난소증후군 환자에서 자 궁내막암 위험이 3~6배가량 높은 것으로 보고된다. 또 다낭난소증후군 환자의 50% 내외에서 인슐린 저항성이 발견되 는데, 이에 따라 40세 이전에 제2형 당뇨병이 생길 수 있다. 다낭난소증후군의 진단 기준은 성인과 청소년기가 다르다. 성인에서는 △희발 월경 혹은 무월경 △임상적 남성 호르몬 과다 증상(다모증, 여드름, 탈모) 또는 혈액검사로 확인된 남성 호르몬 수치 상승 △질식 초음파에서 확인된 다낭 난소 소 견(경우에 따라 초음파 대신 항뮬러관 호르몬 수치로 대체 가능) 이 세 가지 중 두 가지 이상에 해당하면 된다. 하지만 청소년 기에서는 조금 더 신중할 필요가 있다. 초음파 검사를 제외한 두 가지 항목으로 평가를 하고, 진단 기준에 딱 만족하지 않는 경우는 고위험군으로 간주하며 초경 8년 뒤 성인이 되어 재평가가 필요하다. 임신을 원하지 않는 환자는 주기적인 호르몬 치료를 통해 규칙적인 월경을 유도하며, 임신을 원하는 환자는 배란유도제 를 복용하게 된다. 다모증, 여드름이 동반된 환자는 남성 호르몬을 낮출 목적으로 피임약 사용을 고려할 수 있다. 무월 경이 오래 지속된 환자는 자궁내막 증식증의 위험성이 높다. 따라서 초음파 검사를 시행해 자궁내막의 두께를 확인하고 그에 맞춰 조직검사를 시행할 필요도 있다. 무엇보다 생활 습관을 개선하고 체중을 감량하는 것이 중요하다. ‘조기난소부전(Premature Ovarian Failure, Primary Ovarian Insufficiency)’은 흔히 조기 폐경이라고도 불리는 질환이 다. 40세 이전의 젊은 나이에 난소가 제 기능을 하지 않는 것을 의미한다. 조기난소부전이 발생하면 난소가 더 이상 배 란을 하지 않고 여성호르몬도 분비하지 않는다. 따라서 여성호르몬 부족과 관련된 여러 증상과 질환이 나타나게 된다. 조기난소부전의 60%는 그 원인을 알 수 없다. 염색체 이상이나 유전적인 원인은 10%에 해당한다. 수술이나 항암제, 방사선 치료 등이 원인이 될 수 있으며 자가면역질환이 있는 경우에도 영향을 미칠 수 있다. 일반적으로 40세 이하 여성 의 100명 중 1명, 30세 이하 여성의 1,000명 중 1명이 조기난소부전을 경험한다. 조기난소부전 환자는 난소 기능 저하로 인해 월경 간격이 길어지거나 월경을 아예 하지 않는 경우가 많다. 또 여성 호르 몬 감소로 인해 얼굴과 목, 어깨, 등이 후끈 달아오르는 증상(안면홍조, 열성 홍조)이 나타나고 홍조와 함께 땀을 흘리기도 한다. 이외에도 가슴 두근거림(심계 항진), 우울감, 불면증, 관절통, 잦은 소변, 요실금, 성교통, 기억력 감퇴 등이 나타날 수 있다. 난소 기능이 저하됐을 때 증상이 나타나기 때문에 난소 기능이 좋아졌다 나빠지기를 반복하는 경우 증상은 잠 시 나타날 수도 있고, 심하지 않을 수도 있다. 월경주기 변화가 여러 달 동안 있었던 경우 호르몬 검사를 시행해 조기난소부전을 진단하게 된다. 난포자극 호르몬(FSH : Follicle Stimulating Hormone)이라는 검사를 4주 이상 간격으로 2회 이상 시행해 비정상적으로 상승했을 때 진단한다. 최근에는 항뮬러관 호르몬(AMH : Anti-Müllerian Hormone)이라는 검사가 도입돼 난포자극 호르몬이 변화하기 전에 조 금 더 일찍 진단이 가능하게 됐다. 조기난소부전이 확진되면 저용량 호르몬 치료가 권고된다. 이런 증상이 2주 이상 계속된다면?난소 건강을 위해 병원 검진을 받아보자! ➊ 복부 팽만과 불편감 ➋ 극심한 복통 ➌ 복부 압박 증상 ➍ 배변 시의 불편감,배변 장애 ➎ 소화불량 ➏ 심한 생리통 ➐ 성교통 ➑ 비정상적인 출혈 올바른 생활 습관으로 전신 건강 돌봐야 난소는 여성의 신체와 건강 유지에 아주 중요한 기관 중 하나다. 안타깝게도 난소는 그 기능이 한 번 저하되면 회복이 거 의 불가능하다. 특별히 어떤 행동을 한다고 해서 난소를 더 건강하게 만들기는 어렵다. 그러나 흡연과 미세먼지, 비만, 노화, 호르몬 불균형 등이 난소 건강을 저해시킬 수 있는 것으로 알려져 있다. 따라서 교정할 수 있는 요인들은 교정하여 난소 기능이 추가적으로 저하되지 않도록 잘 관리하는 것이 필요하다. 일상에서 금연을 실천하고 미세먼지가 심할 경우 꼭 마스크를 착용해야 한다. 또 비만과 노화, 호르몬 불균형을 예방하기 위해 스트레스를 줄이고 적정 체중 유지에 신경 써야 한다. 금주와 건강한 식생활, 규칙적인 운동 등 건전한 생활 습관을 통해 전신 건강을 챙기는 것이 난소의 건강을 챙기는 길이다. 의료진 소개 산부인과 홍연희 [전문진료분야] 산부인과 : 난임, 가임력보존 (난자동결), 자궁근종, 자궁내막증, 난소낭종 , 로봇수술, 단일절개복강경수술 의료진소개 ※ 해당 기사와 사진은 분당서울대학교병원의 저작물로 임의로 복사, 수정 ,변형, 재가공하여 게시, 배포하였다면 이는 저작권자인 당사의 허가없이 2차저작물을 작성한 것으로 저작권 위반에 해당됩니다.
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- 이른둥이 인공호흡기 떼는 골든타임, 인공지능 모델로 찾는다
- 이른둥이 인공호흡기 떼는 골든타임 인공지능 모델로 찾는다 인터뷰. 소아청소년과 정영화 교수 이른둥이(미숙아)의 인공호흡기 발관(Extubation) 시점은 빨라도, 늦어도 안 된다. 하지만 명확한 기준이 없어 의료진의 판단에 의존하는 실정이다. 이에 소아청소년과 정영화 교수 연구팀이 실시간 생체신호를 분석해 발관 성공률을 예측하는 인공지능 모델을 개발해 냈다. 이를 보조적으로 활용하면 이른둥이의 조기 발관 및 발관 성공률을 높일 수 있을 것으로 기대된다. 이른둥이에게 기도 삽관 후 인공호흡기 사용이 필요한 이유에 관해 설명을 부탁드립니다. 이른 주수에 출생한 이른둥이는 호흡기계의 미성숙으로 호흡곤란이나 잦은 무호흡이 발생할 수 있습니다. 이런 경우 정상적으로 자가호흡이 가능할 때까지 기도 삽관 후 인공 호흡기를 사용해야 합니다. 또한 미성숙한 폐로 인해 신생아중환자실에 입원하는 동안 장기간 침습적 기계환기를 포함한 여러 호흡 보조가 필요한 경우가 많습니다. 특히 주수가 짧을수록, 몸무게가 적을수록 그 빈도가 높아지죠. 최근 신생아학의 발전으로 점점 더 짧은 주수의 이른둥이들이 생존하게 되면서 생후 초기 기도 삽관이 필요한 경우가 늘고 있습니다. 마찬가지로 폐 미성숙에 의해 지속적인 기도 삽관을 유지한 채 인공호흡기 치료가 필요한 경우도 증가하고 있습니다. 이른둥이의 인공호흡기 사용 시 중요한 것은 무엇인가요? 더불어 인공호흡 장치를 제거하는 발관 시점이 왜 중요한지, 시점을 판단하는 데 어떤 어려움이 있는지 말씀해주세요. 이른둥이에게 인공호흡기는 되도록 최소한의 기간만 사용하고 발관하는 것이 좋습니다. 인공호흡기를 통해 숨 쉬는 기간이 필요 이상으로 길어지면 폐가 지속적으로 손상되기 때문입니다. 기관지폐이형성증은 미숙한 폐의 발달 과정 중 지속적인 염증과 손상으로 발생하는데, 기도 삽관 후 장기간 기계환기를 받을수록 이러한 기관지폐이형성증의 발생 위험을 높이고, 신경 발달도 지연시키는 것으로 알려져 있습니다. 따라서 가능하다면 조기에 발관하는 것이 중요합니다. 기관지폐이형성증이란? 주로 초이른둥이에게 발생하는 만성폐질환으로, 호흡곤란이 심해 장기간 인공호흡기 치료나 산소 공급을 받아야 한다. 반면 발관이 너무 이르면 잦은 저산소증과 고이산화탄소혈증이 발생해 뇌에 안 좋은 영향을 끼칠 수 있고, 발관 실패에 이를 수 있습니다. 특히 주수가 이를수록 무호흡 및 여러 다른 동반 질환으로 인해 발관에 실패할 확률이 높아지고, 발관에 실패할 경우 발생하는 혈역학적인 불안정성 역시 환자의 경과를 악화시킬 수 있습니다. 또한 잦은 발관 실패는 그 자체로 기관지폐이형성증의 발생 위험을 증가시킬 수 있어요. 따라서 발관 성공률을 최대한 높이면서, 너무 늦지도, 이르지도 않은 적절한 발관 시점을 찾는 것이 중요합니다. 하지만 아직 발관에 대한 명확한 기준이 없어 센터마다 환자의 임상 상태에 따라 의료진 개개인의 판단에 의존해 발관을 시도하고 있으며, 1,000g 미만의 이른둥이에서 발관 후 이를 유지하는 데 성공할 확률은 평균 60~73% 수준으로 보고되고 있습니다. 고이산화탄소혈증이란? 혈중에 이산화탄소가 비정상으로 증가한 상태. 호흡촉박, 호흡곤란이 발생하고 심하면 의식 상실, 전신 경련이 일어난다. 이른둥이의 발관 시점을 결정하는 데 도움을 주는 인공 지능 모델 ‘넥스트 프리딕터(NExt-Predictor)’를 개발하셨습니다. 연구 과정 및 방법, 기간 등에 관해 설명을 부탁드립니다. 분당서울대병원 신생아중환자실은 고도화된 의료정보시스템을 통해 신생아중환자실에 입원한 환자들의 생체활력징후 등의 정보가 이미 실시간으로 데이터화되고 있습니다. 이 데이터베이스를 이용하여 디지털헬스케어연구사업부 유수영 교수팀과 함께 임상 현장에서 발관 성공률을 실시간 예측할 수 있는 시스템 개발을 계획했습니다. 2003년부터 2019년까지 분당서울대병원에서 태어난 32주 미만의 이른둥이 중 기도 삽관 후 침습적 인공호흡기를 사용한 678명의 데이터를 인공지능을 통해 분석·학습하는 과정을 거쳐, 2022년 안정적인 성능을 보이는 발관 성공 예측 모델 ‘NExt-Predictor’를 개발했습니다. 또 자체 내부 데이터 베이스 및 외부 중환자실 데이터베이스(MIMIC-III)를 이용해 NExt-Predictor가 높은 성능을 보임을 검증했습니다. 발관 성공 예측 모델인 ‘NExt-Predictor’의 특장점이 무엇인지 설명해주세요. NExt-Predictor의 가장 큰 장점은 이미 모니터링하고 있는 생체활력징후 및 의무 기록 정보를 활용해 실시간 성공 예측률을 계산해준다는 것입니다. 따라서 예측을 위해 환자에게 별도의 추가 검사를 시행하거나 추가 장비를 도입할 필요가 없습니다. 또한 환자의 상태 변화를 가장 먼저 보여 주는 것이 생체활력징후이기 때문에 환자의 실시간 상태 변화를 임상 의사가 인지하기 전에 모델에 반영해 예측률을 보여준다는 장점이 있습니다. 이번 연구의 의의가 무엇인지, 해당 결과가 어떻게 활용되길 바라시는지 궁금합니다. 본 연구의 의의는 현재 임상의사 개개인의 판단만으로 이루어지는 발관 시점 결정에 추가적인 도움을 줄 수 있는 AI모델을 개발했다는 점입니다. 이 모델을 임상 판단의 보조적인 근거 수단으로 이용함으로써, 발관의 성공률을 높이는 데 기여할 수 있을 것으로 기대하고 있습니다. 이를 통해 기도 삽관을 한 이른둥이의 조기 발관 및 발관의 성공률을 높이고, 장기적으로 기관지폐이형성증의 발병률을 감소시키는 데 도움을 줄 수 있기를 바랍니다. 향후 추진할 연구나 앞으로의 목표, 계획에 대해 말씀해주십시오. 현재 개발한 AI 모델을 이용한 전향적 임상연구를 계획해 진행 중입니다. 향후 목표는 안정적인 NExt-Predictor의 성능을 확인해 생체활력징후 모니터나 EMR에 반영함으로써 실시간 임상 의사에게 정보를 제공하고 판단에 도움을 주는 것입니다. 마지막으로, <나음 플러스> 독자들에게 전하고 싶은 말씀이 있다면 부탁드립니다. 신생아학의 발전으로 초극소저체중 이른둥이의 생존율이 매우 높아졌으며, 예후 역시 많이 향상됐습니다. 현재 분당서울대병원 신생아중환자실의 의료진들은 이른둥이들이 건강하게 성장할 수 있도록 24시간 치료에 전념하고 있습니다. 앞으로도 아이들의 성장과 발달에 도움이 되도록 연구를 지속해 예후를 향상시키기 위해 노력하겠습니다. 의료진 소개 소아청소년과 정영화 [전문진료분야] 소아청소년과(신생아) : 신생아 및 미숙아, 영유아 질환 의료진소개 ※ 해당 기사와 사진은 분당서울대학교병원의 저작물로 임의로 복사, 수정, 변형, 재가공하여 게시, 배포하였다면 이는 저작권자인 당사의 허가없이 2차저작물을 작성한 것으로 저작권 위반에 해당됩니다.
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- [ 혈액종양내과 (간암센터) ]
- 유방암, 간암의 항암화학요법, 표적요법, 면역요법, 임상시험
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3- 외래진료
- 외래클리닉
- 격주 및 순환진료
안녕하세요? 분당서울대학교병원 혈액종양내과에 근무하고 있는 김지현입니다.
저는 주로 유방암과 간암의 항암치료를 담당하고 있습니다. 암환자의 항암화학요법, 표적요법, 면역요법, 신약 항암제 개발 등을 담당하는 종양내과학 분야는 의학의 발전을 선도하는 가장 눈부시게 발전하고 있는 영역으로, 새로운 정밀 진단법과 여러 새로운 항암제 신약의 개발과 더불어 암 치료 성적은 획기적으로 상승하고 있습니다. 위와 같은 발전에 힘입어 항암치료의 효과와 부작용은 많이 개선되었으며, 많은 암환자분들이 과거에 비하여 안전하고 편안하게 항암치료를 받으실 수 있습니다. 그러나 항암치료는 아직도 많은 환자분들께서 가장 두려워하시는 치료이며, 치료받는 기간 동안 여러 어려움에 직면하게 됩니다. 저는 이 길고 험한 ‘암 여행’의 길을 환자분들과 같이 걸어가는 동반자이자 조언자 역할을 하고자 합니다.
재발과 전이를 겪으신 환자분들께는 하루 하루가 기적이며, 종양내과 의사들의 사명은 이 기적 같은 기간을 보다 더 길게, 편하게, 조금이라도 덜 아프게 해드리는 것입니다. 최근 차세대 염기서열 분석법 (Next generation sequencing)을 이용한 암 유전체검사를 통해 최적의 치료법을 선택하는 이른바 ‘정밀의료’가 도입되면서 기적이 현실이 되는 사례들이 점점 늘어날 것으로 기대하고 있습니다.
암의 치료 성적이 좋아졌다고 모두 다 완치되는 병으로 가볍게 생각하는 것도, 암이나 항암치료를 너무나 두려워하여 치료 시작조차 안하고 포기하는 것도 바람직하지 않습니다. 저는 환자 보호자 의료진이 한마음이 되어 최선을 다하는 것이 암 치료에 있어 그 무엇보다 가장 중요하다고 믿으며, 저희 병원 암센터에서 치료 받으시는 환자분 한 분 한 분께서 모두 행복한 기적의 주인공이 되시기를 기원합니다.
감사합니다.
건강정보
유방암의 항암요법
유방암은 우리나라 여성에서 가장 흔하게 발생하는 암이며 생활습관의 서구화에 따라 그 발생률이 급격하게 증가하고 있습니다. 우리나라 유방암의 특징은 서양보다 발생 연령이 10세 가량 젊은 나이인 40대 후반~50대 초반에 가장 많이 발생한다는 것입니다. 유방암의 경우 완치적 절제술 후 재발방지를 위한 보조항암화학요법 및 호르몬 요법, 표적치료제를 환자분의 종양 특성에 따라 추가로 시행하는 것이 완치율을 향상시키는 것으로 확실히 증명되어 있습니다. 또한 종양의 크기가 크거나 겨드랑이 림프절에 전이가 있는 경우 항암치료를 먼저 시행하여 암의 확산을 막고 종양의 크기를 축소시켜 수술을 용이하게 하는 선행항암요법을 시행하기도 합니다. 전이된 암의 경우라 할지라도 적절한 항암화학요법, 호르몬요법, 표적요법, 면역요법 등을 통하여 삶의 연장 및 삶의 질을 향상시킬 수 있으며, 일부 환자분들은 전이된 상태였더라도 완치되기도 합니다. 다른 암들도 마찬가지이지만 특히 유방암은 하나의 유방암으로 부르지만 그 종류가 매우 다양하여 크게 호르몬 수용체 양성/음성, HER2 양성/음성으로 나누어 치료 방법이 각각 다릅니다. 사람의 생김생김이 한 사람도 똑 같은 사람이 없이 다르듯이 유방암의 성질도 환자분 한 분 한 분마다 모두 다르므로 치료 방법도 달라지게 됩니다.
특히 재발과 전이를 겪으신 환자분들의 경우 항암치료법과 그 부작용이 매우 다양하고 치료를 장기적으로 꾸준히 받으셔야 하기 때문에 의료진과 긴밀한 의사 소통이 중요합니다.
유방암 분야에서는 신약 항암제와 표적치료제의 개발이 가장 앞서서 이루어지고 있어 1상, 2상, 3상 임상시험이 활발하게 진행되고 있습니다. 항암치료가 효과를 나타내기 위하여는 환자분의 몸과 마음을 건강한 상태로 잘 유지하시는 것이 중요하며, 균형 잡힌 식생활과 적절한 운동의 병행을 권합니다.
간암의 항암요법
일반적으로 간암은 항암치료에의 반응이 좋지 않은 것으로 알려져 왔으나 최근 새로운 약제들이 속속 개발되면서 치료 성적이 향상되고 있어 다양한 표적치료와 항암치료를 시행 중입니다. 간세포암의 경우 표적치료제인 소라페님, 렌바티닙, 레고라페닙, 카보잔티닙 등을 사용할 수 있고 최근 면역항암제와의 복합요법이 좋은 효과를 보고하고 있어 새로운 약제의 조합을 이용한 임상시험이 활발하게 진행되고 있습니다. 일부 간기능과 전신상태가 양호하신 환자분들 중에서는 항암화학요법에 좋은 효과를 보이기도 합니다. 간암 환자분들은 B형, C형 간염, 간 경변 등으로 간 기능이 저하되어 있는 경우가 많아 특별히 치료에 주의를 요하며, 분당서울대학교병원에서는 소화기내과와 종양내과, 외과, 방사선 종양학과, 영상의학과, 병리과, 핵의학과에서 다학제 진료팀을 이루어 최적의 치료법을 논의하고 있습니다.
정밀의료 다학제 클리닉
정밀의료 다학제 클리닉에서는 차세대 염기서열 분석 기반 종양 유전체 검사를 시행하고 그 결과를 토대로 종양내과, 생물정보학자, 병리과, 진단검사의학과 등 관련 전문가들이 협의 진료를 통해 암환자분들께 가장 적절한 치료를 추천합니다. 또한 유전성 암 다학제 클리닉에서는 관련 의료진들이 모여 유전성 암환자들을 대상으로 다양한 예방적 치료와 조기 진단을 위한 검사를 시행하며, 가족 검사와 카운셀링을 제공합니다.
노인암 다학제 클리닉
고령화의 진행과 함께 노인 암 환자가 증가하고 있습니다. 암은 나이가 많을수록 발생이 증가하는 이른바 노인병이며, 노인 암환자분들은 젊은 환자들과 달리 여러 장기의 기능이 저하되거나 동반질환을 앓고 계신 분이 많아 치료 결정에 있어 더욱 주의가 필요합니다. 분당서울대학교병원에서는 노인포괄평가를 시행하여 노인 암환자들의 전신 상태를 평가하고 노인병내과와의 협진과 노인암 다학제 진료를 시행함으로써 노인 암환자의 최적의 치료법을 찾아가고 있습니다.
직위 ●
- 서울대학교 의과대학 교수
- 분당서울대학교병원 혈액종양내과 교수
- 분당서울대학교병원 임상유전체의학과장
- 분당서울대학교병원 연구기획부 부장
학력 ●
- 1995 서울대학교 의학과 학사
- 2002 서울대학교 의과대학원 내과학 석사
- 2004 서울대학교 의과대학원 내과학 박사
경력 ●
- 1997 - 2001 서울대학교병원 내과 전공의
- 2001 - 2002 서울대학교병원 혈액종양내과 전임의
- 2002 - 2003 보라매병원 혈액종양내과 전문의
- 2003 - 2008 분당서울대학교병원 혈액종양내과 조교수
- 2008 - 2009 Dana Farber Cancer Institute, Havard Medical School Department of Molecular and Cellular Oncology Visiting Professor
- 2009 - 2015 분당서울대학교병원 혈액종양내과 부교수
- 2015 - 현재 분당서울대학교병원 혈액종양내과 교수
- 2017 - 2020 분당서울대학교병원 임상시험센터장
- 2019 - 2024 분당서울대학교병원 임상정밀의료센터장
- 2020 - 2021 분당서울대학교병원 정밀의료센터장
- 2022 - 현재 분당서울대학교병원 미래혁신연구부장
- 2024 - 현재 분당서울대학교병원 임상유전체의학과장
수상
활동 ●
- 대한종양내과학회 정회원, 상임이사
- 대한항암요법연구회 정회원, 이사, 교육위원장
- 대한암학회 정회원, 이사
- 대한내과학회 정회원
- American Society of Clinical Oncology (ASCO) 정회원
- American Association for Cancer Research (AACR) 정회원
- International Society of Geriatric Oncology (SIOG) 정회원
논문 ●
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Ji Yun Lee, Ju-Hyun Lee, Sang-A Kim, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jeong-Ok Lee, Jin Won Kim, Yu Jung Kim, Keun-Wook Lee, Jee Hyun Kim, Jong Seok Lee, Soo-Mee Bang
Treatment patterns of thrombopoietin receptor agonists among adults with primary immune thrombocytopenia: A Korean nationwide population-based study.
Thromb Res
2022 ;213 :114 -118
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Yu Jung Kim, Seok Joon Yoon, Sang-Yeon Suh, Yusuke Hiratsuka, Beodeul Kang, Si Won Lee, Hong-Yup Ahn, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Keun-Wook Lee, Jee Hyun Kim, Jong Seok Lee
Performance of clinician prediction of survival in oncology outpatients with advanced cancer.
PLoS One
2022 ;17 (4) :e0267467 -e0267467
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Minsu Kang, Koung Jin Suh, Ji-Won Kim, Ja Min Byun, Jin Won Kim, Ji Yun Lee, Jeong-Ok Lee, Soo-Mee Bang, Yu Jung Kim, Se Hyun Kim, Jee Hyun Kim, Jong Seok Lee, Keun-Wook Lee
Clinical characteristics and disease course of splanchnic vein thrombosis in gastrointestinal cancers: A prospective cohort study.
PLoS One
2022 ;17 (1) :e0261671 -e0261671
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Javier Cortes, Sung-Bae Kim, Wei-Pang Chung, Seock-Ah Im, Yeon Hee Park, Roberto Hegg, Min Hwan Kim, Ling-Ming Tseng, Vanessa Petry, Chi-Feng Chung, Hiroji Iwata, Erika Hamilton, Giuseppe Curigliano, Binghe Xu, Chiun-Sheng Huang, Jee Hyun Kim, Joanne W Y Chiu, Jose Luiz Pedrini, Caleb Lee, Yali Liu, Jillian Cathcart, Emarjola Bako, Sunil Verma, Sara A Hurvitz, DESTINY-Breast03 Trial Investigators
Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer.
N Engl J Med
2022 ;386 (12) :1143 -1154
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Eun Hee Jung, Si Won Lee, Yu Jung Kim, Beodeul Kang, Koung Jin Suh, Ju Hyun Lee, Esther Jeon, Dahee Kim, Sung Soun Hur, Ji Yun Lee, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Jeong-Ok Lee, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jong Seok Lee, Eduardo Bruera
Clinical Outcomes of Operating an Acute Palliative Care Unit at a Comprehensive Cancer Center.
JCO Oncol Pract
2022 ;18 (10) :e1661 -e1671
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Hee Kyung Ahn, Sung Hoon Sim, Koung Jin Suh, Min Hwan Kim, Jae Ho Jeong, Ji-Yeon Kim, Dae-Won Lee, Jin-Hee Ahn, Heejung Chae, Kyung-Hun Lee, Jee Hyun Kim, Keun Seok Lee, Joo Hyuk Sohn, Yoon-La Choi, Seock-Ah Im, Kyung Hae Jung, Yeon Hee Park
Response Rate and Safety of a Neoadjuvant Pertuzumab, Atezolizumab, Docetaxel, and Trastuzumab Regimen for Patients With ERBB2-Positive Stage II/III Breast Cancer: The Neo-PATH Phase 2 Nonrandomized Clinical Trial.
JAMA Oncol
2022 ;8 (9) :1271 -1277
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Koung Jin Suh, Se Hyun Kim, Yu Jung Kim, Heechul Shin, Eunyoung Kang, Eun-Kyu Kim, Sejoon Lee, Ji Won Woo, Hee Young Na, Soomin Ahn, Bum-Sup Jang, In Ah Kim, So Yeon Park, Jee Hyun Kim
Clinical Application of Next-Generation Sequencing in Patients With Breast Cancer: Real-World Data.
J Breast Cancer
2022 ;25 (5) :366 -378
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Minsu Kang, Hee Young Na, Soomin Ahn, Ji-Won Kim, Sejoon Lee, Soyeon Ahn, Ju Hyun Lee, Jeonghwan Youk, Haesook T Kim, Kui-Jin Kim, Koung Jin Suh, Jun Suh Lee, Se Hyun Kim, Jin Won Kim, Yu Jung Kim, Keun-Wook Lee, Yoo-Seok Yoon, Jee Hyun Kim, Jin-Haeng Chung, Ho-Seong Han, Jong Seok Lee
Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors.
Elife
2022 ;11
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Jae Sik Kim, Kyubo Kim, Wonguen Jung, Kyung Hwan Shin, Seock-Ah Im, Hee-Jun Kim, Yong Bae Kim, Jee Suk Chang, Jee Hyun Kim, Doo Ho Choi, Yeon Hee Park, Dae Yong Kim, Tae Hyun Kim, Byung Ock Choi, Sea-Won Lee, Suzy Kim, Jeanny Kwon, Ki Mun Kang, Woong-Ki Chung, Kyung Su Kim, Ji Ho Nam, Won Sup Yoon, Jin Hee Kim, Jihye Cha, Yoon Kyeong Oh, In Ah Kim
The Pattern of Care for Brain Metastasis from Breast Cancer over the Past 10 Years in Korea: A Multicenter Retrospective Study (KROG 16-12).
Cancer Res Treat
2022 ;54 (4) :1121 -1129
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Shinkyo Yoon, Miso Kim, Yong Sang Hong, Han Sang Kim, Seung Tae Kim, Jihun Kim, Hongseok Yun, Changhoon Yoo, Hee Kyung Ahn, Hyo Song Kim, In Hee Lee, In-Ho Kim, Inkeun Park, Jae Ho Jeong, Jaekyung Cheon, Jin Won Kim, Jina Yun, Sun Min Lim, Yongjun Cha, Se Jin Jang, Dae Young Zang, Tae Won Kim, Jin Hyoung Kang, Jee Hyun Kim
Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group.
Cancer Res Treat
2022 ;54 (1) :1 -9
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Yu Jung Kim, Yusuke Hiratsuka, Sang-Yeon Suh, Beodeul Kang, Si Won Lee, Hong-Yup Ahn, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Keun-Wook Lee, Jee Hyun Kim, Jong Seok Lee
A Prognostic Model to Facilitate Palliative Care Referral in Oncology Outpatients.
Cancer Res Treat
2022 ;54 (2) :621 -629
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Song Yi Park, Koung Jin Suh, Dae-Won Lee, Han Suk Ryu, Miso Kim, Se Hyun Kim, Kyung-Hun Lee, Tae-Yong Kim, Jee Hyun Kim, In Ae Park, Seock-Ah Im
Prognostic role of tumor subtype and germline BRCA mutation in advanced breast cancer patients treated with palbociclib plus endocrine therapy.
Breast Cancer Res Treat
2022 ;196 (1) :121 -128
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Sung Hoon Sim, Jeong Eun Kim, Min Hwan Kim, Yeon Hee Park, Jee Hyun Kim, Koung Jin Suh, Su-Jin Koh, Kyong Hwa Park, Myoung Joo Kang, Mi Sun Ahn, Kyoung Eun Lee, Hee-Jun Kim, Hee Kyung Ahn, Han Jo Kim, Keon Uk Park, Jae Ho Byun, Jin Hyun Park, Gyeong-Won Lee, Keun Seok Lee, Joohyuk Sohn, Kyung Hae Jung, In Hae Park
Phase II study to investigate the efficacy of trastuzumab biosimilar (Herzuma®) plus treatment of physician's choice (TPC) in patients with heavily pretreated HER-2+ metastatic breast cancer (KCSG BR 18-14/KM10B).
Breast
2022 ;65 (0) :172 -178
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Soohyeon Lee, Kyunghee Park, Gun Min Kim, Kyung Hae Jung, Seok Yun Kang, In Hae Park, Jee Hyun Kim, Hee Kyung Ahn, Woong-Yang Park, Seock-Ah Im, Yeon Hee Park
Exploratory analysis of biomarkers associated with clinical outcomes from the study of palbociclib plus endocrine therapy in premenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer.
Breast
2022 ;62 (0) :52 -60
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Jung-Yeon Choi, Ji Yeon Lee, Jaeyong Shin, Chang Oh Kim, Kwang Joon Kim, In Gyu Hwang, Yun-Gyoo Lee, Su-Jin Koh, Soojung Hong, Sol-Ji Yoon, Min-Gu Kang, Jin Won Kim, Jee Hyun Kim, Kwang-Il Kim
COMPrehensive geriatric AsseSSment and multidisciplinary team intervention for hospitalised older adults (COMPASS): a protocol of pragmatic trials within a cohort.
BMJ Open
2022 ;12 (8) :e060913 -e060913
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In Jun Yang, Heung-Kwon Oh, Jeehye Lee, Jung Wook Suh, Hong-Min Ahn, Hye Rim Shin, Jin Won Kim, Jee Hyun Kim, Changhoon Song, Jung-Yeon Choi, Duck-Woo Kim, Sung-Bum Kang
Efficacy of geriatric multidisciplinary oncology clinic in the surgical treatment decision-making process for frail elderly patients with colorectal cancer.
Ann Surg Treat Res
2022 ;103 (3) :169 -175
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Jung Rae Cho, Keun-Wook Lee, Heung-Kwon Oh, Jin Won Kim, Ji-Won Kim, Duck-Woo Kim, Jee Hyun Kim, Sung-Bum Kang
Effectiveness of oral fluoropyrimidine monotherapy as adjuvant chemotherapy for high-risk stage II colon cancer.
Ann Surg Treat Res
2022 ;102 (5) :271 -280
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Yu Jung Kim, Yusuke Hiratsuka, Sang-Yeon Suh, Seon-Hye Won, Eun Hee Jung, Beodeul Kang, Si Won Lee, Hong-Yup Ahn, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Keun-Wook Lee, Jee Hyun Kim, Jong Seok Lee
Performance of mid-upper arm circumference and other prognostic indices based on inflammation and nutrition in oncology outpatients: a tertiary cancer center study.
Ann Palliat Med
2022 ;11 (10) :3171 -3180
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Jwa Hoon Kim, Seyoung Seo, Jee Hyun Kim, Su-Jin Koh, Yongchel Ahn, Kyung Hae Jung, Jin-Hee Ahn, Sung-Bae Kim, Tae Won Kim, Yong Sang Hong, Sun Young Kim, Jeong Eun Kim, Sang-We Kim, Dae Ho Lee, Jae Cheol Lee, Chang-Min Choi, Shinkyo Yoon, Jae Ho Jeong, Hwa Jung Kim, Koung Jin Suh, Se Hyun Kim, Yu Jung Kim, Young Joo Min, Jin Ho Baek, Sook Ryun Park
The impact of systematic assessment for adverse events on unscheduled hospital utilization in patients receiving neoadjuvant or adjuvant chemotherapy: A retrospective multicenter study.
Cancer Med
2022 ;11 (3) :705 -714
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Jung Sun Kim, Koung Jin Suh, Dae-Won Lee, Go-Un Woo, Miso Kim, Se Hyun Kim, Han Suk Ryu, Kyung-Hun Lee, Tae-Yong Kim, Sae-Won Han, So Yeon Park, In Ae Park, Jee Hyun Kim, Seock-Ah Im
A Real-world Efficacy of Nab-paclitaxel Monotherapy in Metastatic Breast Cancer.
Cancer Res Treat
2022 ;54 (2) :488 -496
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Kyung-Hwak Yoon, Yeshong Park, Eunyoung Kang, Eun-Kyu Kim, Jee Hyun Kim, Se Hyun Kim, Koung Jin Suh, Sun Mi Kim, Mijung Jang, Bo La Yun, So Yeon Park, Hee-Chul Shin
Effect of Estrogen Receptor Expression Level and Hormonal Therapy on Prognosis of Early Breast Cancer.
Cancer Res Treat
2021
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In Gyu Hwang, Minsuk Kwon, Jin Won Kim, Se Hyun Kim, Yun-Gyoo Lee, Jin Young Kim, Su-Jin Koh, Yoon Ho Ko, Seong Hoon Shin, Soojung Hong, Tae-Yong Kim, Sun Young Kim, Hyun Jung Kim, Hyo Jung Kim, Myung Ah Lee, Jung Hye Kwon, Yong Sang Hong, Kyung Hee Lee, Sung Hwa Bae, Dong-Hoe Koo, Jee Hyun Kim, In Sook Woo
Prevalence and Predictive Factors for Upfront Dose Reduction of the First Cycle of First-Line Chemotherapy in Older Adults with Metastatic Solid Cancer: Korean Cancer Study Group (KCSG) Multicenter Study.
Cancers (Basel)
2021 ;13 (2)
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Jee Hyun Kim, Seock Ah Im, Sung Hoon Sim, Eustratios Bananis, Xin Huang, Hyun Seon Kim, Sung Bae Kim
Palbociclib Plus Fulvestrant in Korean Patients from PALOMA-3 With Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer.
J Breast Cancer
2021 ;24 (1) :97 -105
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Byung Seok Moon, Hyun Soo Park, Jung Sunwoo, In-Hyun Lee, Anhye Kim, Seol Ju Moon, Heechan Lee, Min Hee Son, Su Bin Kim, Sun Mi Park, Sang-Keun Woo, Jun-Hee Jang, Bom Sahn Kim, Jee Hyun Kim, Sang Eun Kim, Howard Lee
Tissue pharmacokinetics of DHP107, a novel lipid-based oral formulation of paclitaxel, in mice and patients by positron emission tomography.
Clin Transl Sci
2021 ;14 (5) :1747 -1755
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Ji Yun Lee, Jin Ho Paik, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Yu Jung Kim, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jong-Seok Lee, Jeong-Ok Lee
R-MPV followed by high-dose chemotherapy with thiotepa-based and autologous stem cell transplantation for newly diagnosed primary central nervous system lymphoma: a single-center experience.
Blood Res
2021 ;56 (4) :285 -292
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Koung Jin Suh, Seonghae Yoon, Jin Won Kim, Seo Hyun Yoon, Ji-Won Kim, Se Hyun Kim, Yu Jung Kim, Keun-Wook Lee, Jong Seok Lee, Jee Hyun Kim
A single-arm feasibility study of gradual dose de-escalation of antiemetic dexamethasone for older patients receiving chemotherapy.
J Geriatr Oncol
2021 ;12 (6) :922 -929
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Kyung-Hun Lee, Eui Kyu Chie, Seock-Ah Im, Jee Hyun Kim, Jihyun Kwon, Sae-Won Han, Do-Youn Oh, Jin-Young Jang, Jae-Sung Kim, Tae-You Kim, Yung-Jue Bang, Sun Whe Kim, Sung W Ha
Phase II Trial of Postoperative Adjuvant Gemcitabine and Cisplatin Chemotherapy Followed by Chemoradiotherapy with Gemcitabine in Patients with Resected Pancreatic Cancer.
Cancer Res Treat
2021 ;53 (4) :1096 -1103
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Jae Sik Kim, Kyubo Kim, Wonguen Jung, Kyung Hwan Shin, Seock-Ah Im, Hee-Jun Kim, Yong Bae Kim, Jee Suk Chang, Jee Hyun Kim, Doo Ho Choi, Yeon Hee Park, Dae Yong Kim, Tae Hyun Kim, Byung Ock Choi, Sea-Won Lee, Suzy Kim, Jeanny Kwon, Ki Mun Kang, Woong-Ki Chung, Kyung Su Kim, Won Sup Yoon, Jin Hee Kim, Jihye Cha, Yoon Kyeong Oh, In Ah Kim
New brain metastases after whole-brain radiotherapy of initial brain metastases in breast cancer patients: the significance of molecular subtypes (KROG 16-12).
Breast Cancer Res Treat
2021 ;186 (2) :453 -462
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Sang-A Kim, Hyejoo Park, Kui-Jin Kim, Ji-Won Kim, Ji Hea Sung, Milang Nam, Ju Hyun Lee, Eun Hee Jung, Koung Jin Suh, Ji Yun Lee, Se Hyun Kim, Jeong-Ok Lee, Jin Won Kim, Yu Jung Kim, Jee Hyun Kim, Soo-Mee Bang, Jong Seok Lee, Keun-Wook Lee
Amphiregulin can predict treatment resistance to palliative first-line cetuximab plus FOLFIRI chemotherapy in patients with RAS wild-type metastatic colorectal cancer.
Sci Rep
2021 ;11 (1) :23803 -23803
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Yul Ri Chung, Ji Won Woo, Soomin Ahn, Eunyoung Kang, Eun-Kyu Kim, Mijung Jang, Sun Mi Kim, Se Hyun Kim, Jee Hyun Kim, So Yeon Park
Prognostic implications of regression of metastatic axillary lymph nodes after neoadjuvant chemotherapy in patients with breast cancer.
Sci Rep
2021 ;11 (1) :12128 -12128
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Ji Yun Lee, Minsu Kang, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Yu Jung Kim, Kyoung-Ho Song, Eu Suk Kim, Hong Bin Kim, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jong-Seok Lee, Jeong-Ok Lee
Pneumocystis jirovecii pneumonia in diffuse large B-cell Lymphoma treated with R-CHOP.
Mycoses
2021 ;64 (1) :60 -65
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E H Cho, J-Y Kim, S-A Im, K H Jung, J Sohn, K S Lee, Y S Chae, K H Lee, J H Kim, J-H Jang, J H Ahn, M S Park, S-Y Lee, Y H Park
Potential role of CMPK1, SLC29A1, and TLE4 polymorphisms in gemcitabine-based chemotherapy in HER2-negative metastatic breast cancer patients: pharmacogenetic study results from the prospective randomized phase II study of eribulin plus gemcitabine versus paclitaxel plus gemcitabine (KCSG-BR-13-11).
ESMO Open
2021 ;6 (5) :100236 -100236
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Baek-Yeol Ryoo, Ann-Li Cheng, Zhenggang Ren, Tae-You Kim, Hongming Pan, Kun-Ming Rau, Hye Jin Choi, Joong-Won Park, Jee Hyun Kim, Chia Jui Yen, Ho Yeong Lim, Dongli Zhou, Josef Straub, Juergen Scheele, Karin Berghoff, Shukui Qin
Randomised Phase 1b/2 trial of tepotinib vs sorafenib in Asian patients with advanced hepatocellular carcinoma with MET overexpression.
Br J Cancer
2021 ;125 (2) :200 -208
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In Sil Choi, Ki Hwan Kim, Ju Hyun Lee, Koung Jin Suh, Ji-Won Kim, Jin Hyun Park, Yu Jung Kim, Jin-Soo Kim, Jee Hyun Kim, Jin Won Kim
A randomised phase II study of oxaliplatin/5-FU (mFOLFOX) versus irinotecan/5-FU (mFOLFIRI) chemotherapy in locally advanced or metastatic biliary tract cancer refractory to first-line gemcitabine/cisplatin chemotherapy.
Eur J Cancer
2021 ;154 :288 -295
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Yen-Shen Lu, Keun Seok Lee, Tsu-Yi Chao, Ling-Ming Tseng, Imjai Chitapanarux, Shin-Cheh Chen, Chien-Ting Liu, Joohyuk Sohn, Jee Hyun Kim, Yuan-Ching Chang, Youngsen Yang, Kanjana Shotelersuk, Kyung Hae Jung, Roberta Valenti, Cassandra Slader, Melissa Gao, Yeon Hee Park
A Phase Ib Study of Alpelisib or Buparlisib Combined with Tamoxifen Plus Goserelin in Premenopausal Women with HR-Positive HER2-Negative Advanced Breast Cancer.
Clin Cancer Res
2021 ;27 (2) :408 -417
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Ji Won Park, Sung-Bum Kang, Jie Hao, Seok-Byung Lim, Hyo Seong Choi, Duck-Woo Kim, Hee Jin Chang, Dae Yong Kim, Kyung Hae Jung, Tae-You Kim, Gyeong Hoon Kang, Eui Kyu Chie, Sun Young Kim, Dae Kyung Sohn, Jae-Sung Kim, Hye Seung Lee, Jee Hyun Kim, Seung-Yong Jeong, Jae Hwan Oh
Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): 10-year follow-up of an open-label, non-inferiority, randomised controlled trial.
Lancet Gastroenterol Hepatol
2021 ;6 (7) :569 -577
-
Tae Kyu Chung, Hyun A Lee, Sang-In Park, Do-Youn Oh, Keun-Wook Lee, Jin Won Kim, Jee Hyun Kim, Ahmi Woo, Su Jin Lee, Yung-Jue Bang, Howard Lee
A target-mediated drug disposition population pharmacokinetic model of GC1118, a novel anti-EGFR antibody, in patients with solid tumors.
Clin Transl Sci
2021 ;14 (3) :990 -1001
-
KimJi-Yeon, ParkKyunghee, ImSeock-Ah, JungKyung Hae, SohnJoohyuk, LeeKeun Seok, KimJee Hyun, YangYaewon, ParkYeon Hee
Clinical implications of HER2 mRNA expression and intrinsic subtype in refractory HER2-positive metastatic breast cancer treated with pan-HER inhibitor, poziotinib.
Breast Cancer Res Treat
2020 ;184 (3) :743 -753
-
JEE HYUN KIM, Chung Tae Kyu, Lee Howard, Lee Hyun A, Park Sang-In, Oh Do-Youn, Lee Keun-Wook, Kim Jin Won, Woo Ahmi, Lee Su Jin, Bang Yung-Jue
A target-mediated drug disposition population pharmacokinetic model of GC1118, a novel anti-EGFR antibody, in patients with solid tumors
CTS-CLIN TRANSL SCI
2020 ;14 (3) :990 -1001
-
Soohyeon Lee, Seock-Ah Im, Gun Min Kim, Kyung Hae Jung, Seok Yun Kang, In Hae Park, Jee Hyun Kim, Kyoung Eun Lee, Hee Kyung Ahn, Moon Hee Lee, Hee-Jun Kim, Han Jo Kim, Jong In Lee, Su-Jin Koh, Yeon Hee Park
Patient-Reported Outcomes of Palbociclib Plus Exemestane with GnRH Agonist versus Capecitabine in Premenopausal Women with Hormone Receptor-Positive Metastatic Breast Cancer: A Prospective, Open-Label, Randomized Phase ll Trial (KCSG-BR 15-10).
Cancers (Basel)
2020 ;12 (11)
-
Hyun Jung Lee, Kui-Jin Kim, Ji Hea Sung, Milang Nam, Koung Jin Suh, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Yu Jung Kim, Keun-Wook Lee, Jong Seok Lee, Jee Hyun Kim
PI3K p110α Blockade Enhances Anti-Tumor Efficacy of Abemaciclib in Human Colorectal Cancer Cells.
Cancers (Basel)
2020 ;12 (9)
-
Se Hyun Kim, Soomin Ahn, Koung Jin Suh, Yu Jung Kim, So Yeon Park, Eunyoung Kang, Eun-Kyu Kim, In Ah Kim, Sumin Chae, Murim Choi, Jee Hyun Kim
Identifying germline APOBEC3B deletion and immune phenotype in Korean patients with operable breast cancer.
Breast Cancer Res Treat
2020 ;183 (3) :697 -704
-
Kui-Jin Kim, Ji-Won Kim, Ji Hea Sung, Koung Jin Suh, Ji Yun Lee, Se Hyun Kim, Jeong-Ok Lee, Jin Won Kim, Yu Jung Kim, Jee Hyun Kim, Soo-Mee Bang, Jong Seok Lee, Hark Kyun Kim, Keun-Wook Lee
PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer.
Sci Rep
2020 ;10 (1) :12308 -12308
-
Hyung-Don Kim, Yeonghak Bang, Myung Ah Lee, Jin Won Kim, Jee Hyun Kim, Hong Jae Chon, Beodeul Kang, Myoung Joo Kang, Ilhwan Kim, Jaekyung Cheon, Jun-Eul Hwang, Jung Hun Kang, Seonggyu Byeon, Jung Yong Hong, Baek-Yeol Ryoo, Ho Yeong Lim, Changhoon Yoo
Regorafenib in patients with advanced Child-Pugh B hepatocellular carcinoma: A multicentre retrospective study.
Liver Int
2020 ;40 (10) :2544 -2552
-
Changhoon Yoo, Seonggyu Byeon, Yeonghak Bang, Jaekyung Cheon, Jin W Kim, Jee H Kim, Hong J Chon, Beodeul Kang, Myoung J Kang, Ilhwan Kim, Jun-Eul Hwang, Jung H Kang, Myung A Lee, Jung Y Hong, Ho Y Lim, Baek-Yeol Ryoo
Regorafenib in previously treated advanced hepatocellular carcinoma: Impact of prior immunotherapy and adverse events.
Liver Int
2020 ;40 (9) :2263 -2271
-
Sang-A Kim, Ji-Won Kim, Koung Jin Suh, Won Chang, Jin Won Kim, Heung-Kwon Oh, Jai Young Cho, Duck-Woo Kim, Sukki Cho, Jee Hyun Kim, Kwhanmien Kim, Sung-Bum Kang, Sanghoon Jheon, Keun-Wook Lee
Conversion surgery after cetuximab or bevacizumab plus FOLFIRI chemotherapy in colorectal cancer patients with liver- and/or lung-limited metastases.
J Cancer Res Clin Oncol
2020 ;146 (9) :2399 -2410
-
Grace S Ahn, Hak Ro Kim, Beodeul Kang, Sung Soun Hur, Ji-Won Kim, Se Hyun Kim, Jin Won Kim, Jeong-Ok Lee, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jong Seok Lee, Yu Jung Kim
Symptom burden and characteristics of patients who die in the acute palliative care unit of a tertiary cancer center.
Ann Palliat Med
2020 ;9 (2) :216 -223
-
Soojung Hong, Ju Hyun Lee, Eun Kyeong Chun, Kwang-Il Kim, Jin Won Kim, Se Hyun Kim, Yun-Gyoo Lee, In Gyu Hwang, Jin Young Kim, Su-Jin Koh, Yoon Ho Ko, Seong Hoon Shin, In Sook Woo, Tae-Yong Kim, Ji Yeon Baek, Hyun Jung Kim, Hyo Jung Kim, Myung Ah Lee, Jung Hye Kwon, Yong Sang Hong, Hun-Mo Ryoo, Jee Hyun Kim
Polypharmacy, Inappropriate Medication Use, and Drug Interactions in Older Korean Patients with Cancer Receiving First-Line Palliative Chemotherapy.
Oncologist
2020 ;25 (3) :e502 -e511
-
Y H Park, E Senkus-Konefka, S-A Im, G Pentheroudakis, S Saji, S Gupta, H Iwata, M Y Mastura, R Dent, Y-S Lu, Y Yin, B K Smruti, T Toyama, S Malwinder, S C Lee, L-M Tseng, J H Kim, T-Y Kim, K J Suh, F Cardoso, T Yoshino, J-Y Douillard
Pan-Asian adapted ESMO Clinical Practice Guidelines for the management of patients with early breast cancer: a KSMO-ESMO initiative endorsed by CSCO, ISMPO, JSMO, MOS, SSO and TOS.
Ann Oncol
2020 ;31 (4) :451 -469
-
Jin Won Kim, Ahrum Min, Seock-Ah Im, Hyemin Jang, Yu Jin Kim, Hee-Jun Kim, Kyung-Hun Lee, Tae-Yong Kim, Keun Wook Lee, Do-Youn Oh, Jee-Hyun Kim, Yung-Jue Bang
TDP1 and TOP1 Modulation in Olaparib-Resistant Cancer Determines the Efficacy of Subsequent Chemotherapy.
Cancers (Basel)
2020 ;12 (2)
-
Soomin Ahn, Hyun Jeong Kim, Eunyoung Kang, Eun-Kyu Kim, Se Hyun Kim, Jee Hyun Kim, In Ah Kim, So Yeon Park
Genomic profiling of multiple breast cancer reveals inter-lesional heterogeneity.
Br J Cancer
2020 ;122 (5) :697 -704
-
Choe Hun Jee, Kim Jin Won, Han Song-Hee, Lee Ju Hyun, Ahn Sang-Hoon, Park Do Joong, Kim Ji-Won, Kim Yu Jung, Lee Hye Seung, Kim Jee Hyun, Kim Hyung-Ho, Lee Keun-Wook
Conversion Surgery in Metastatic Gastric Cancer and Cancer Dormancy as a Prognostic Biomarker
CANCERS
2019 ;12 (1)
-
Yoon Kyung-Hwak, Kim Eun-Kyu, Chae Sumin, Kang Eunyoung, Shin Hee-Chul, Kim Jee Hyun, Kim In Ah, Park So Yeon, Kim Sung-Won
Contralateral Breast Cancer and Ipsilateral Breast Tumor Recurrence in BRCA1/2 Carriers and Non-Carriers at High-Risk of Hereditary Breast Cancer
J BREAST CANCER
2019 ;22 (4) :587 -598
-
Kwon Ji-Hyun, Lee Jong Seok, Kim Kui-Jin, Sung Ji Hea, Suh Koung Jin, Lee Ji Yun, Kim Ji-Won, Kim Se Hyun, Lee Jeong-Ok, Kim Jin Won, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Kim Soyeon, Yoon Sung-Soo
Afatinib Overcomes Pemetrexed-Acquired Resistance in Non-Small Cell Lung Cancer Cells Harboring an EML4-ALK Rearrangement
CELLS-BASEL
2019 ;8 (12)
-
Choi Yeonjoo, Kim Jin Won, Suh Koung Jin, Lim Yoo-Joo, Lee Ji Yun, Kang Beo-Deul, Kim Ji-Won, Kim Se-Hyun, Lee Jeong-Ok, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Lee Jong Seok
Identification of a potentially avoidable cardiopulmonary resuscitation in hematology and oncology wards
BMC PALLIAT CARE
2019 ;18 (1)
-
Park Yeon Hee, Im Seock-Ah, Kim Tae-Yong, Kim Gun Min, Kang Seok Yun, Park In Hae, Kim Jee Hyun, Lee Kyoung Eun, Ahn Hee Kyung, Lee Moon Hee, Kim Hee-Jun, Kim Han Jo, Lee Jong In, Koh Su-Jin, Kim Ji-Yeon, Lee Kyung-Hun, Sohn Joohyuk, Kim Sung-Bae, Ahn Jin-Seok, Im Young-Hyuck, Jung Kyung Hae,
Palbociclib plus exemestane with gonadotropin-releasing hormone agonist versus capecitabine in premenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer (KCSG-BR15-10): a multicentre, open-label, randomised, phase 2 trial
LANCET ONCOL
2019 ;20 (12) :1750 -1759
-
Woo Ji Won, Park So Yeon, Chung Yul Ri, Ahn Soomin, Kang Eunyoung, Kim Eun-Kyu, Kim Se Hyun, Kim Jee Hyun, Kim In Ah
Changes in Biomarker Status in Metastatic Breast Cancer and Their Prognostic Value
J BREAST CANCER
2019 ;22 (3) :439 -452
-
Kim Ji-Yeon, Park Yeon Hee, Lee Eunjin, Park Kyunghee, Im Seock-Ah, Sohn Joohyuk, Lee Keun Seok, Chae Yee Soo, Kim Jee Hyun, Kim Tae-Yong, Jung Kyung Hae,
Exploratory biomarker analysis from a phase II clinical trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine for HER2-negative metastatic breast cancer patients (KCSG BR13-11)
BREAST CANCER RES TR
2019 ;178 (2) :367 -377
-
Im Seock-Ah, Lee Dae-Won, Kang Ryungwoo, Kim Jee Hyun, Kim Dong-Wan, Jang In-Jin, Lee Jong-Seok, Bang Yung-Jue
Challenges and insights of early oncology drug development in the Asia-Pacific region: introduction of phase I oncology clinical trial center and experience sharing for early clinical trials in Seoul National University Hospital, Korea
Chin Clin Oncol
2019 ;8 (3)
-
Choe Hun Jee, Suh Koung Jin, Lee Ji Yun, Kim Minyoung, Kim Man Jin, Park Sung Sup, Kim Ji-Won, Kim Se Hyun, Kim Jin Won, Lee Jeong-Ok, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Lee Jong Seok
Acute pulmonary thromboembolism caused by factor V Leiden mutation in South Korea: A case report
MEDICINE
2019 ;98 (28)
-
Han Song-Hee, Kim Jin Won, Shin Eun, Kim Milim, Kim Jee Hyun, Lee Keun-Wook, Kim Bo-Hyung, Oh Heung-Kwon, Kim Duck-Woo, Kang Sung-Bum, Kim Hyunchul
Prognostic implication of ABC transporters and cancer stem cell markers in patients with stage III colon cancer receiving adjuvant FOLFOX-4 chemotherapy
ONCOL LETT
2019 ;17 (6) :5572 -5580
-
Kim Ji-Yeon, Park Yeon Hee, Park Seri, Im Seock-Ah, Kim Sung-Bae, Sohn Joohyuk, Lee Keun Seok, Chae Yee Soo, Lee Ki Hyeong, Kim Jee Hyun, Im Young-Hyuck, Kim Tae-Yong, Lee Kyung-Hun, Ahn Jin-Hee, Kim Gun Min, Park In Hae, Lee Soo Jung, Han Hye Sook, Kim Se Hyun, Jung Kyung Hae,
Quality of life outcomes including neuropathy-associated scale from a phase II, multicenter, randomized trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine as first-line chemotherapy for HER2-negative metastatic breast cancer: Korean Cancer Study Group Trial (KCSG BR13-11)
CANCER COMMUN
2019 ;39 (1)
-
Kim Se Hyun, Kim Jin Won, Hwang In Gyu, Jang Joung Soon, Hong Soojung, Kim Tae-Yong, Baek Ji Yeon, Shin Seong Hoon, Sun Der Sheng, Hong Dae-Sik, Kim Hyo Jung, Hong Yong Sang, Woo In Sook, Lee Ju-Hyun, Kim Jee Hyun
Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors
J GERIATR ONCOL
2019 ;10 (5) :749 -756
-
Han Jae Joon, Kim Jin Won, Suh Koung Jin, Kim Ji-Won, Kim Se Hyun, Kim Yu Jung, Kim Jee Hyun, Lee Jong Seok, Lee Keun-Wook
Clinical characteristics and outcomes of patients enrolled in clinical trials compared with those of patients outside clinical trials in advanced gastric cancer
ASIA-PAC J CLIN ONCO
2019 ;15 (3) :158 -165
-
Kim Ji-Yeon, Lee Eunjin, Park Kyunghee, Jung Hae Hyun, Park Woong-Yang, Lee Kyung-Hun, Sohn Joohyuk, Lee Keun Seok, Jung Kyung Hae, Kim Jee Hyun, Lee Ki Hyeong, Im Seock-Ah, Park Yeon Hee
Molecular alterations and poziotinib efficacy, a pan-HER inhibitor, in human epidermal growth factor receptor 2 (HER2)-positive breast cancers: Combined exploratory biomarker analysis from a phase II clinical trial of poziotinib for refractory HER2-positive breast cancer patients
INT J CANCER
2019 ;145 (6) :1669 -1678
-
Kim Jin Won, Kim Se Hyun, Lee Yun-Gyoo, Hwang In Gyu, Kim Jin Young, Koh Su-Jin, Ko Yoon Ho, Shin Seong Hoon, Woo In Sook, Hong Soojung, Kim Tae-Yong, Baek Ji Yeon, Kim Hyun Jung, Kim Hyo Jung, Lee Myung Ah, Kwon Jung Hye, Hong Yong Sang, Ryoo Hun-Mo, Lee Kyung Hee, Kim Jee Hyun
Prospective Validation of The Korean Cancer Study Group Geriatric Score (KG)-7, a Novel Geriatric Screening Tool, in Older Patients with Advanced Cancer Undergoing First-line Palliative Chemotherapy
CANCER RES TREAT
2019 ;51 (3) :1249 -1256
-
Shin Junghoon, Chung Jin-Haeng, Kim Se Hyun, Lee Kyu Sang, Suh Koung Jin, Lee Ji Yun, Kim Ji-Won, Lee Jeong-Ok, Kim Jin-Won, Kim Yu-Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Lee Jong-Seok
Effect of Platinum-Based Chemotherapy on PD-L1 Expression on Tumor Cells in Non-small Cell Lung Cancer
CANCER RES TREAT
2019 ;51 (3) :1086 -1097
-
Lee Jeong-Ok, Bang Soo-Mee, Lee Ji Yun, Chun Eun Ju, Choi Sang Il, Kim Jin Won, Kim Se Hyun, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Lee Jong Seok
Incidence and predictors of venous thromboembolism in medically ill hospitalized elderly cancer patients: a prospective observational study
SUPPORT CARE CANCER
2019 ;27 (7) :2507 -2515
-
Yoo Changhoon, Ryoo Baek-Yeol, Kang Jihoon, Lim Ho Yeong, Kim Jee Hyun, Lee Myung-Ah, Lee Kyung-Hun, Kim Tae-You
Phase I Dose-Finding Study of OPB-111077, a Novel STAT3 Inhibitor, in Patients with Advanced Hepatocellular Carcinoma
CANCER RES TREAT
2019 ;51 (2) :510 -518
-
Park In Hae, Im Seock-Ah, Jung Kyung Hae, Sohn Joo Hyuk, Park Yeon Hee, Lee Keun Seok, Sim Sung Hoon, Park Kyong-Hwa, Kim Jee Hyun, Nam Byung Ho, Kim Hee-Jun, Kim Tae-Yong, Lee Kyung-Hun, Kim Sung-Bae, Ahn Jin-Hee, Lee Suee, Ro Jungsil
Randomized Open Label Phase III Trial of Irinotecan Plus Capecitabine versus Capecitabine Monotherapy in Patients with Metastatic Breast Cancer Previously Treated with Anthracycline and Taxane: PROCEED Trial (KCSG BR 11-01)
CANCER RES TREAT
2019 ;51 (1) :43 -52
-
Jeon Wan, Jang Bum-Sup, Jeon Seung Hyuck, Kim Jee Hyun, Kim Yu Jung, Kim Se Hyun, Kim Chae-Yong, Han Jung Ho, Kim In Ah
Analysis of survival outcomes based on molecular subtypes in breast cancer brain metastases: A single institutional cohort
BREAST J
2018 ;24 (6) :920 -926
-
Choi In Sil, Kim Jee Hyun, Lee Ju Hyun, Suh Koung Jin, Lee Ji Yun, Kim Ji-Won, Kim Se-Hyun, Kim Jin Won, Lee Jeong-Ok, Kim Yu Jung, Bang Soo-Mee, Lee Jong Seok, Lee Keun-Wook
A population-based outcomes study of patients with metastatic gastric cancer receiving second-line chemotherapy: A nationwide health insurance database study
PLOS ONE
2018 ;13 (10)
-
Kim Se Hyun, Ryu Haram, Ock Chan-Young, Suh Koung Jin, Lee Ji Yun, Kim Ji-Won, Lee Jeong-Ok, Kim Jin Won, Kim Yu Jung, Lee Keun-Wook, Bang Soo-Mee, Kim Jee Hyun, Lee Jong Seok, Ahn Joong Bae, Kim Kui-Jin, Rha Sun Young
BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression
INT J MOL SCI
2018 ;19 (10)
-
Kim Ji-Yeon, Im Seock-Ah, Jung Kyung Hae, Ro Jungsil, Sohn Joohyuk, Kim Jee Hyun, Park Yeon Hee, Kim Tae-Yong, Kim Sung-Bae, Lee Keun Seok, Kim Gun Min, Kim Se Hyun, Kim Seonwoo, Ahn Jin Seok, Lee Kyung-Hun, Ahn Jin-Hee, Park In Hae, Im Young-Hyuck,
Fulvestrant plus goserelin versus anastrozole plus goserelin versus goserelin alone for hormone receptor-positive, HER2-negative tamoxifen-pretreated premenopausal women with recurrent or metastatic breast cancer (KCSG BR10-04): a multicentre, open-label, three-arm, randomised phase II trial (FLAG study)
EUR J CANCER
2018 ;103 :127 -136
-
Song Changhoon, Chung Joo-Hyun, Kang Sung-Bum, Kim Duck-Woo, Oh Heung-Kwon, Lee Hye Seung, Kim Jin Won, Lee Keun-Wook, Kim Jee Hyun, Kim Jae-Sung
Impact of Tumor Regression Grade as a Major Prognostic Factor in Locally Advanced Rectal Cancer after Neoadjuvant Chemoradiotherapy: A Proposal for a Modified Staging System
CANCERS
2018 ;10 (9)
-
Lee Yun-Gyoo, Lee Ju Hyun, Kim Se-Hyun, Kim Yu Jung, Lee Heeyoung, Ahn Soyeon, Jang Joung-Soon, Lee Jong-Seok, Kim Jee Hyun
Comparative analysis between combination and single-agent chemotherapy for elderly patients with advanced non-small cell lung cancer: A nationwide population-based outcome study
LUNG CANCER
2018 ;122 :88 -93
-
Park Yeon Hee, Lee Kyung-Hun, Sohn Joo Hyuk, Lee Keun Seok, Jung Kyung Hae, Kim Jee-Hyun, Lee Ki Hyeong, Ahn Jin Seok, Kim Tae-Yong, Kim Gun Min, Park In Hae, Kim Sung-Bae, Kim Se Hyun, Han Hye Sook, Im Young-Hyuck, Ahn Jin-Hee, Kim Jung-Yong, Kang Jahoon, Im Seock-Ah
A phase II trial of the pan-HER inhibitor poziotinib, in patients with HER2-positive metastatic breast cancer who had received at least two prior HER2-directed regimens: results of the NOV120101-203 trial
INT J CANCER
2018 ;143 (12) :3240 -3247
-
Kim Milim, Kim Hyun Jeong, Chung Yul Ri, Kang Eunyoung, Kim Eun-Kyu, Kim Se Hyun, Kim Yu Jung, Kim Jee Hyun, Kim In Ah, Park So Yeon
Microinvasive Carcinoma versus Ductal Carcinoma In Situ: A Comparison of Clinicopathological Features and Clinical Outcomes
J BREAST CANCER
2018 ;21 (2) :197 -205
-
Kim Hye Jin, Kang Eunyoung, Kim Jee Hyun, Kim Se Hyun, Kim Yu Jung, Kim In Ah, Eom Keun-Yong, Chae Su Min, Kang Kyu Min, Kim Eun Kyu, Kim Sung-Won
Survival Benefit of Surgical Removal of Primary Tumor in Patients With Stage IV Breast Cancer
CLIN BREAST CANCER
2018 ;18 (5) :e1037 -e1044
-
Choi In Sil, Choi Mihong, Lee Ju Hyun, Kim Jee Hyun, Suh Koung Jin, Lee Ji Yun, Kang Beodeul, Kim Ji-Won, Kim Se-Hyun, Kim Jin Won, Lee Jeong-Ok, Kim Yu Jung, Bang Soo-Mee, Lee Jong Seok, Lee Keun-Wook
Treatment patterns and outcomes in patients with metastatic gastric cancer receiving third-line chemotherapy: A population-based outcomes study
PLOS ONE
2018 ;13 (6)
-
Chae S, Kang K M, Kim H J, Kang E, Park S Y, Kim J H, Kim S H, Kim S W, Kim E K
Neutrophil-lymphocyte ratio predicts response to chemotherapy in triple-negative breast cancer
CURR ONCOL
2018 ;25 (2) :e113 -e119
-
Kim Jin Won, Lee Yun-Gyoo, Hwang In Gyu, Song Hong Suk, Koh Su Jin, Ko Yoon Ho, Shin Seong Hoon, Woo In Sook, Hong Soojung, Kim Tae-Yong, Kim Sun Young, Nam Byung-Ho, Kim Hyun Jung, Kim Hyo Jung, Lee Myung Ah, Kwon Jung Hye, Hong Yong Sang, Bae Sung Hwa, Koo Dong-Hoe, Kim Kwang-Il, Kim Jee Hyun
Predicting cumulative incidence of adverse events in older patients with cancer undergoing first-line palliative chemotherapy: Korean Cancer Study Group (KCSG) multicentre prospective study
BRIT J CANCER
2018 ;118 (9) :1169 -1175
-
Lee Dae-Won, Lee Kyung-Hun, Kim Hee-Jun, Kim Tae-Yong, Kim Jin-Soo, Han Sae-Won, Oh Do-Youn, Kim Jee Hyun, Im Seock-Ah, Kim Tae-You
A phase II trial of S-1 and oxaliplatin in patients with advanced hepatocellular carcinoma
BMC CANCER
2018 ;18 (1)
-
Ahn Soomin, Kim Hyun Jeong, Kim Milim, Chung Yul Ri, Kang Eunyoung, Kim Eun-Kyu, Kim Se Hyun, Kim Yu Jung, Kim Jee Hyun, Kim In Ah, Park So Yeon
Negative Conversion of Progesterone Receptor Status after Primary Systemic Therapy Is Associated with Poor Clinical Outcome in Patients with Breast Cancer
CANCER RES TREAT
2018 ;50 (4) :1418 -1432
-
Lim Yu Jin, Lee Sea-Won, Choi Noorie, Kwon Jeanny, Eom Keun-Yong, Kang Eunyoung, Kim Eun-Kyu, Kim Jee Hyun, Kim Yu Jung, Kim Se Hyun, Park So Yeon, Kim In Ah
A Novel Prognostic Nomogram for Predicting Risks of Distant Failure in Patients with Invasive Breast Cancer Following Postoperative Adjuvant Radiotherapy
CANCER RES TREAT
2018 ;50 (4) :1140 -1148
-
Kim Tae Min, Bang Yung-Jue, Lee Keun-Wook, Oh Do-Youn, Lee Jong-Seok, Im Seock-Ah, Kim Dong-Wan, Han Sae-Won, Kim Yu Jung, Kim Tae-You, Kim Jee Hyun, Han Hyesun, Kim Woo Ho
Phase 1 Studies of Poziotinib, an Irreversible Pan-HER Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors
CANCER RES TREAT
2018 ;50 (3) :835 -842
-
Koh Su-Jin, Kim Shinmi, Kim JinShil, Keam Bhumsuk, Heo Dae Seog, Lee Kyung Hee, Kim Bong-Seog, Kim Jee Hyun, Chang Hye Jung, Baek Sun Kyung
Experiences and Opinions Related to End-of-Life Discussion: From Oncologists' and Resident Physicians' Perspectives
CANCER RES TREAT
2018 ;50 (2) :614 -623
-
Kim Tackeun, Song Changhoon, Han Jung Ho, Kim In-Ah, Kim Yu Jung, Kim Se Hyun, Kim Jee Hyun, Kim Chae-Yong
Epidemiology of Intracranial Metastases in Korea: A National Cohort Investigation
CANCER RES TREAT
2018 ;50 (1) :164 -174
-
JEE HYUN KIM
노인 암 환자의 접근과 관리 원칙
대한두경부종양학회지
2017 ;33 (2) :1 -8
-
Iwata Hiroji, Im Seock-Ah, Masuda Norikazu, Im Young-Hyuck, Inoue Kenichi, Rai Yoshiaki, Nakamura Rikiya, Kim Jee Hyun, Hoffman Justin T, Zhang Ke, Giorgetti Carla, Iyer Shrividya, Schnell Patrick T, Bartlett Cynthia Huang, Ro Jungsil
PALOMA-3: Phase III Trial of Fulvestrant With or Without Palbociclib in Premenopausal and Postmenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer That Progressed on Prior Endocrine Therapy-Safety and Efficacy in Asian Patients
J Glob Oncol
2017 ;3 (4) :289 -303
-
Park Jin Hyun, Choi In Sil, Kim Ki Hwan, Kim Jin-Soo, Lee Kyung-Hun, Kim Tae-Yong, Im Seock-Ah, Kim Se Hyun, Kim Yu Jung, Kim Jee Hyun
Treatment Patterns and Outcomes in Elderly Patients with Metastatic Breast Cancer: A Multicenter Retrospective Study
J BREAST CANCER
2017 ;20 (4) :368 -377
-
Park Yeon Hee, Jung Kyung Hae, Im Seock-Ah, Kim Sung-Bae, Sohn Joo Hyuk, Lee Keun Seok, Chae Yee Soo, Lee Ki Hyeong, Kim Jee Hyun, Im Young-Hyuck, Kim Ji-Yeon, Kim Tae-Yong, Lee Kyung-Hun, Ahn Jin-Hee, Kim Gun Min, Park In Hae, Lee Soo Jung, Han Hye Sook, Kim Se Hyun,
Phase II, multicentre, randomised trial of eribulin plus gemcitabine versus paclitaxel plus gemcitabine as first-line chemotherapy in patients with HER2-negative metastatic breast cancer
EUR J CANCER
2017 ;86 :385 -393
-
Kim Se Hyun, Lee Jong Seok, Kim Mi-Jung, Kim Yu Jung, Chang Hyun, Kim Jin Won, Lee Jeong-Ok, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee
Paclitaxel as third-line chemotherapy for small cell lung cancer failing both etoposide- and camptothecin-based chemotherapy
MEDICINE
2017 ;96 (42)
-
Suh Koung Jin, Kim Jin Won, Sung Ji Hea, Han Song-Hee, Lee Hye Seung, Min Ahrum, Kang Mi Hyun, Kim Ji Eun, Kim Ji-Won, Kim Se Hyun, Lee Jeong-Ok, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Im Seock-Ah, Lee Jong Seok
EGFR or HER2 inhibition modulates the tumor microenvironment by suppression of PD-L1 and cytokines release
Oncotarget
2017 ;8 (38) :63901 -63910
-
Park Sehhoon, Kim Jin Won, Kim Haeryoung, Kim Ji-Won, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Kim Jai Hwan, Hwang Jin-Hyeok, Choi Young Rok, Cho Jai Young, Yoon Yoo-Seok, Han Ho-Seong
Prognostic value of p21-activated kinase 4 in resected pancreatic cancer
APMIS
2017 ;125 (8) :699 -707
-
Lee Ji Yun, Bang Soo-Mee, Lee Ju-Hyun, Lee Heeyoung, Kang Beodeul, Kim Ji-Won, Kim Se Hyun, Lee Jeong-Ok, Kim Jin Won, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Choi Hyoung Soo, Lee Jong Seok
Epidemiology and management of primary immune thrombocytopenia: A nationwide population-based study in Korea
THROMB RES
2017 ;155 :86 -91
-
Lim Yu Jin, Kim In Ah, Lee Sea-Won, Choi Noorie, Kwon Jeanny, Eom Keun-Yong, Kang Eunyoung, Kim Eun-Kyu, Kim Sung-Won, Kim Jee Hyun, Kim Yu Jung, Kim Se Hyun, Park So Yeon, Kim Jae-Sung
Failure patterns according to molecular subtype in patients with invasive breast cancer following postoperative adjuvant radiotherapy: long-term outcomes in contemporary clinical practice
BREAST CANCER RES TR
2017 ;163 (3) :555 -563
-
Suh Koung Jin, Kim Se Hyun, Lee Kyung-Hun, Kim Tae-Yong, Kim Yu Jung, Han Sae-Won, Kang Eunyoung, Kim Eun-Kyu, Kim Kidong, No Jae Hong, Han Wonshik, Noh Dong-Young, Lee Maria, Kim Hee Seung, Im Seock-Ah, Kim Jee Hyun
Bilateral Salpingo-oophorectomy Compared to Gonadotropin-Releasing Hormone Agonists in Premenopausal Hormone Receptor-Positive Metastatic Breast Cancer Patients Treated with Aromatase Inhibitors
CANCER RES TREAT
2017 ;49 (4) :1153 -1163
-
Kim Ji-Won, Lee Keun-Wook, Kim Kyu-Pyo, Lee Ju Hyun, Hong Yong Sang, Kim Jeong-Eun, Kim Sun Young, Park Sook Ryun, Nam Byung-Ho, Cho Sang-Hee, Chung Ik-Joo, Park Young Suk, Oh Ho-Suk, Lee Myung-Ah, Kang Hye Jin, Park Young Iee, Song Eun-Kee, Han Hye Sook, Lee Kyu Taeg, Shin Dong Bok, Kang Jung Hun, Zang Dae Young, Kim Jee Hyun, Kim Tae Won
Efficacy and Safety of FOLFIRI Regimen in Elderly Versus Nonelderly Patients with Metastatic Colorectal or Gastric Cancer
ONCOLOGIST
2017 ;22 (3) :293 -303
-
Lee Dae-Won, Im Seock-Ah, Kim Yu Jung, Yang Yaewon, Rhee Jiyoung, Na Im Il, Lee Kyung-Hun, Kim Tae-Yong, Han Sae-Won, Choi In Sil, Oh Do-Youn, Kim Jee Hyun, Kim Tae-You, Bang Yung-Jue
CA19-9 or CEA Decline after the First Cycle of Treatment Predicts Survival in Advanced Biliary Tract Cancer Patients Treated with S-1 and Cisplatin Chemotherapy
CANCER RES TREAT
2017 ;49 (3) :807 -815
-
Yoo Shin Hye, Kim Se Hyun, Kim Hyean-Ji, Kim Jeong-Han, Lee Gyeong-Won, Lee Jeong Hee, Kim Ji-Won, Kim Jin Won, Lee Jeong-Ok, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Lee Jong Seok
Nephrotic syndrome associated with metastatic thymoma treated with chemotherapy
MEDICINE
2017 ;96 (1)
-
Lee Kyuongyul, Park So Yeon, Jang Min Hye, Chung Yul Ri, Lee Yangkyu, Kang Eunyoung, Kim Sung-Won, Kim Yu Jung, Kim Jee Hyun, Kim In Ah
Prognostic significance of centromere 17 copy number gain in breast cancer depends on breast cancer subtype
HUM PATHOL
2017 ;61 :111 -120
-
Lim Yoojoo, Kim Tae-You, Bang Ji-In, Han Sae-Won, Paeng Jin Chul, Lee Kyung-Hun, Kim Jee Hyun, Kang Gyeong Hoon, Jeong Seung-Yong, Park Kyu Joo
Total lesion glycolysis (TLG) as an imaging biomarker in metastatic colorectal cancer patients treated with regorafenib
EUR J NUCL MED MOL I
2017 ;44 (5) :757 -764
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Kim Seongyeong, Min Ahrum, Lee Kyung-Hun, Yang Yaewon, Kim Tae-Yong, Lim Jee Min, Park So Jung, Nam Hyun-Jin, Kim Jung Eun, Song Sang-Hyun, Han Sae-Won, Oh Do-Youn, Kim Jee Hyun, Kim Tae-You, Hangauer David, Lau Johnson Yiu-Nam, Im Kyongok, Lee Dong Soon, Bang Yung-Jue, Im Seock-Ah
Antitumor Effect of KX-01 through Inhibiting Src Family Kinases and Mitosis
CANCER RES TREAT
2017 ;49 (3) :643 -655
-
Park Yeon Hee, Jung Kyung Hae, Kim Tae Yong, Im Young-Hyuck, Lee Keun-Seok, Park In Hae, Sohn Joohyuk, Lee Soo-Hyeon, Im Seock-Ah, Kim Jee Hyun, Kim Se Hyun, Lee Soo Jung, Koh Su-Jin, Lee Ki Hyeong, Choi Yoon Ji, Cho Eun Kyung, Lee Suee, Kang Seok Yun, Seo Jae Hong, Kim Sung-Bae
Feasibility and Efficacy of Eribulin Mesilate in Korean Patients with Metastatic Breast Cancer: Korean Multi-center Phase IV Clinical Study Results
CANCER RES TREAT
2017 ;49 (2) :423 -429
-
Cha Yongjun, Kim Yu Jung, Lee Se-Hoon, Kim Tae-Min, Choi Seung Hong, Kim Dong-Wan, Park Chul-Kee, Kim Il Han, Kim Jee Hyun, Kim Eunhee, Choi Byungse, Kim Chae-Yong, Kim In Ah, Heo Dae Seog
Post-bevacizumab Clinical Outcomes and the Impact of Early Discontinuation of Bevacizumab in Patients with Recurrent Malignant Glioma
CANCER RES TREAT
2017 ;49 (1) :129 -140
-
Kim Jin Won, Lee Keun-Wook, Nam Kyung Han, Ahn Sang-Hoon, Park Do Joong, Kim Hyung-Ho, Kim Se Hyun, Chang Hyun, Lee Jeong-Ok, Kim Yu Jung, Lee Hye Seung, Kim Jee Hyun, Bang Soo-Mee, Lee Jong Seok
Prognostic implications of immunosuppressive protein expression in tumors as well as immune cell infiltration within the tumor microenvironment in gastric cancer
GASTRIC CANCER
2016 ;19 (1) :42 -52
-
Oh Do-Youn, Kim Tae-Min, Han Sae-Won, Shin Dong-Yeop, Lee Yun Gyoo, Lee Keun-Wook, Kim Jee Hyun, Kim Tae-You, Jang In-Jin, Lee Jong-Seok, Bang Yung-Jue
Phase I Study of CKD-516, a Novel Vascular Disrupting Agent, in Patients with Advanced Solid Tumors
CANCER RES TREAT
2016 ;48 (1) :28 -36
-
Yoo Changhoon, Kim Sung-Bae, Ro Jungsil, Im Seock-Ah, Im Young-Hyuck, Kim Jee Hyun, Ahn Jin-Hee, Jung Kyung Hae, Song Hong Suk, Kang Seok Yun, Park Hee Sook, Chung Hyun-Cheol
Circulating Plasma Biomarkers for TSU-68, an Oral Antiangiogenic Agent, in Patients with Metastatic Breast Cancer
CANCER RES TREAT
2016 ;48 (2) :499 -507
-
Kim Ji-Won, Im Seock-Ah, Kim Debora K, Min Ahrum, Lee Kyung-Hun, Nam Hyun-Jin, Kim Jee Hyun, Kim Jin-Soo, Kim Tae-Yong, Park In Ae
Amphiregulin confers trastuzumab resistance via AKT and ERK activation in HER2-positive breast cancer
J CANCER RES CLIN
2016 ;142 (1) :157 -165
-
Lee Ki Hyeong, Oh Do-Youn, Im Seock-Ah, Kim Ji-Yeon, Lee Moon Hee, Han Hye Sook, Lim Joo Han, Park Keon Uk, Park In Hae, Cho Eun Kyung, Yoon So Young, Kim Jee Hyun, Choi In Sil, Park Jae Hoo, Choi Young Jin, Kim Hee-Jun, Jung Kyung Hae, Kim Si-Young
A randomized, multicenter, phase II/III study to determine the optimal dose and to evaluate the efficacy and safety of pegteograstim (GCPGC) on chemotherapy-induced neutropenia compared to pegfilgrastim in breast cancer patients: KCSG PC10-09
SUPPORT CARE CANCER
2016 ;24 (4) :1709 -1717
-
Lee Eunyoung, Kang Sung-Bum, Choi Sang Il, Chun Eun Ju, Kim Min Jeong, Kim Duck-Woo, Oh Heung-Kwon, Ihn Myong Hoon, Kim Jin Won, Bang Soo-Mee, Lee Jeong-Ok, Kim Yu Jung, Kim Jee Hyun, Lee Jong Seok, Lee Keun-Wook
Prospective Study on the Incidence of Postoperative Venous Thromboembolism in Korean Patients with Colorectal Cancer
CANCER RES TREAT
2016 ;48 (3) :978 -989
-
Jung Hee-Won, Kim Jin Won, Kim Ki Woong, Han Ji Won, Kim Kayoung, Kim Jee Hyun, Kim Kwang-Il, Kim Cheol-Ho
Multidimensional Geriatric Prognostic Index, Based on a Geriatric Assessment, for Long-Term Survival in Older Adults in Korea
PLOS ONE
2016 ;11 (1)
-
Kang Mi Hyun, Moon Sung Ung, Sung Ji Hea, Kim Jin Won, Lee Keun Wook, Lee Hye Seung, Lee Jong Seok, Kim Jee Hyun
Antitumor Activity of HM781-36B, alone or in Combination with Chemotherapeutic Agents, in Colorectal Cancer Cells
CANCER RES TREAT
2016 ;48 (1) :355 -364
-
Lee Yoon Hyun, Oh Heung-Kwon, Kim Duck-Woo, Ihn Myong Hoon, Kim Jee Hyun, Son Il Tae, Kang Sung Il, Kim Gwang Il, Ahn Soyeon, Kang Sung-Bum
Use of a Comprehensive Geriatric Assessment to Predict Short-Term Postoperative Outcome in Elderly Patients With Colorectal Cancer
Ann Coloproctol
2016 ;32 (5) :161 -169
-
Choi Younak, Kim Jee Hyun, Kim Ji-Won, Kim Jin Won, Lee Keun-Wook, Oh Heung-Kwon, Kim Duck-Woo, Kang Sung-Bum, Song Changhoon, Kim Jae-Sung
Preoperative chemoradiotherapy for elderly patients with locally advanced rectal cancer-a real-world outcome study
JPN J CLIN ONCOL
2016 ;46 (12) :1108 -1117
-
Keefe Dorothy, Al Garni Abdullah, Villalon Antonio, Hassan Azza, Kwong Dora, Li Pingping, Tamura Kazuo, Kim Jee Hyun, Yusof Mastura Md, Javed Muhammad Zafar, Kanesvaran Ravindran, Hsieh Ruey-Kuen, Aapro Matti
Challenges in supportive cancer care: perspectives from the Asia Pacific and Middle East
SUPPORT CARE CANCER
2016 ;24 (11) :4479 -4481
-
Seo An Na, Park So Yeon, Lee Hee Jin, Kim Eun Joo, Jang Min Hye, Kim Yu Jung, Kim Jee Hyun, Kim Sung-Won, Ryu Han Suk, Park In Ae, Im Seock-Ah, Gong Gyungyub, Jung Kyung Hae, Kim Hee Jeong
Expression of breast cancer stem cell markers as predictors of prognosis and response to trastuzumab in HER2-positive breast cancer
BRIT J CANCER
2016 ;114 (10) :1109 -1116
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Kim Se Hyun, Jung Kyung Hae, Kim Tae-Yong, Im Seock-Ah, Choi In Sil, Chae Yee Soo, Baek Sun Kyung, Kang Seok Yun, Park Sarah, Park In Hae, Lee Keun Seok, Choi Yoon Ji, Lee Soohyeon, Sohn Joo Hyuk, Park Yeon-Hee, Im Young-Hyuck, Ahn Jin-Hee, Kim Sung-Bae, Kim Jee Hyun
Prognostic Value of Axillary Nodal Ratio after Neoadjuvant Chemotherapy of Doxorubicin/Cyclophosphamide Followed by Docetaxel in Breast Cancer: A Multicenter Retrospective Cohort Study
CANCER RES TREAT
2016 ;48 (4) :1373 -1381
-
Eom Keun-Yong, Jang Min Hye, Park So Yeon, Kang Eun Young, Kim Sung Won, Kim Jee Hyun, Kim Jae-Sung, Kim In Ah
The Expression of Carbonic Anhydrase (CA) IX/XII and Lymph Node Metastasis in Early Breast Cancer
CANCER RES TREAT
2016 ;48 (1) :125 -132
-
Lee Keun-Wook, Lee Ju Hyun, Kim Jin Won, Kim Ji-Won, Ahn Soyeon, Kim Jee Hyun
Population-based outcomes research on treatment patterns and impact of chemotherapy in older patients with metastatic gastric cancer
J CANCER RES CLIN
2016 ;142 (3) :687 -697
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Lim Yoojoo, Han Sae-Won, Yoon Jeong Hee, Lee Jeong Min, Lee Jung Min, Paeng Jin Chul, Won Jae-Kyung, Kang Gyeong Hoon, Jeong Seung-Yong, Park Kyu Joo, Lee Kyung-Hun, Kim Jee Hyun, Kim Tae-You
Clinical Implication of Anti-Angiogenic Effect of Regorafenib in Metastatic Colorectal Cancer
PLOS ONE
2015 ;10 (12)
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Park Younghee, Kim In Ah, Lee Kyu Sang, Park So Yeon, Kim Jee Hyun, Kang Eun Young, Kim Sung Won, Eom Keon Young, Kim Jae Sung
Potential Prognostic Value of Histone Deacetylase 6 and Acetylated Heat-Shock Protein 90 in Early-Stage Breast Cancer
J BREAST CANCER
2015 ;18 (3) :249 -255
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Cho Kyoung-Min, Kim Yu Jung, Kim Se Hyun, Kim Jin Won, Lee Jeong-Ok, Han Jung Ho, Lee Keun-Wook, Kim Jee Hyun, Kim Chae-Yong, Bang Soo-Mee, Kim In-Ah, Kim Jae Sung, Lee Jong-Seok
Salvage Treatment with Intracerebrospinal Fluid Thiotepa in Patients with Leptomeningeal Metastasis After Failure of Methotrexate-based Treatment
ANTICANCER RES
2015 ;35 (10) :5631 -5638
-
Kim Jin Won, Kim Se-Hyun, Kim Yu Jung, Lee Keun-Wook, Kim Kwang-Il, Lee Jong Seok, Kim Cheol-Ho, Kim Jee Hyun,
A Novel Geriatric Screening Tool in Older Patients with Cancer: The Korean Cancer Study Group Geriatric Score (KG)-7
PLOS ONE
2015 ;10 (9)
-
Koo Taeryool, Song Changhoon, Kim Jae-Sung, Kim Kyubo, Chie Eui Kyu, Kang Sung-Bum, Lee Keun-Wook, Kim Jee Hyun, Jeong Seung-Yong, Kim Tae-You
Impact of Lymph Node Ratio on Oncologic Outcomes in ypStage III Rectal Cancer Patients Treated with Neoadjuvant Chemoradiotherapy followed by Total Mesorectal Excision, and Postoperative Adjuvant Chemotherapy
PLOS ONE
2015 ;10 (9)
-
Park Yeon Hee, Jung Kyung Hae, Im Seock-Ah, Sohn Joo Hyuk, Ro Jungsil, Ahn Jin-Hee, Kim Sung-Bae, Nam Byung-Ho, Oh Do Youn, Han Sae-Won, Lee Soohyeon, Park In Hae, Lee Keun Seok, Kim Jee Hyun, Kang Seok Yun, Lee Moon Hee, Park Hee Sook, Woo Sook Young, Jung Sin-Ho, Ahn Jin Seok, , Im Young-Hyuck
Quality of life (QoL) in metastatic breast cancer patients with maintenance paclitaxel plus gemcitabine (PG) chemotherapy: results from phase III, multicenter, randomized trial of maintenance chemotherapy versus observation (KCSG-BR07-02)
BREAST CANCER RES TR
2015 ;152 (1) :77 -85
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Song Changhoon, Song Sanghyuk, Kim Jae-Sung, Oh Heung-Kwon, Kim Duck-Woo, Lee Keun-Wook, Kim Jee Hyun, Eom Keun-Yong, Kim In Ah, Kang Sung-Bum
Impact of Postoperative Chemoradiotherapy versus Chemotherapy Alone on Recurrence and Survival in Patients with Stage II and III Upper Rectal Cancer: A Propensity Score-Matched Analysis
PLOS ONE
2015 ;10 (4)
-
Lee Yoontaek, Kang Eunyoung, Lee Angela Soeun, Baek Hyunnam, Kim Eun-Kyu, Park So Yeon, Kim Jee Hyun, Kim Yu Jung, Kim Se Hyun, Kim In Ah, Eom Keun-Yong, Kim Sung-Won
Outcomes and recurrence patterns according to breast cancer subtypes in Korean women
BREAST CANCER RES TR
2015 ;151 (1) :183 -190
-
Hong Sukho, Jeong Sook-Hyang, Lee Sang Soo, Chung Jung Wha, Yang Sung Wook, Chung Seong Min, Jang Eun Sun, Kim Jin-Wook, Kim Jee Hyun, Kim Haeryoung, Cho Jai Young, Yoon Yoo-Seok, Han Ho-Seong
Prevalence and outcomes of extrahepatic primary malignancy associated with hepatocellular carcinoma in a Korean population
BMC CANCER
2015 ;15
-
Kim Jin Won, Choi In Sil, Kim Yu Jung, Lee Kyung-Hun, Lee Keun-Wook, Kim Tae-Yong, Han Sae-Won, Kim Jee Hyun, Kim Tae-You, Lee Jong Seok, Bang Yung-Jue, Im Seock-Ah, Oh Do-Youn
A phase I/II trial of second-line chemotherapy with paclitaxel and irinotecan in fluoropyrimidine- and platinum-pretreated patients with advanced gastric cancer
CANCER CHEMOTH PHARM
2015 ;75 (6) :1175 -1182
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Kim Ji-Yeon, Shin Eun, Lee Keun-Wook, Kim Jin Won, Lee Hye Seung, Lee Dae-Won, Kim Se-Hyun, Lee Jeong-Ok, Kim Yu Jung, Kim Jee Hyun, Bang Soo-Mee, Ahn Sang-Hoon, Park Do Joong, Lee Jong Seok, Lee Ju-Seog, Kim Hyung-Ho
Impact of intratumoral expression levels of fluoropyrimidine-metabolizing enzymes on treatment outcomes of adjuvant S-1 therapy in gastric cancer
PLOS ONE
2015 ;10 (3)
-
Moon Sung-Ung, Kim Jin Won, Sung Ji Hea, Kang Mi Hyun, Kim Se-Hyun, Chang Hyun, Lee Jeong-Ok, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Lee Jong Seok
p21-Activated Kinase 4 (PAK4) as a Predictive Marker of Gemcitabine Sensitivity in Pancreatic Cancer Cell Lines
CANCER RES TREAT
2015 ;47 (3) :501 -508
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Yoshida Taku, Kim Jee Hyun, Carver Kristopher, Su Ying, Weremowicz Stanislawa, Mulvey Laura, Yamamoto Shoji, Brennan Cameron, Mei Shenglin, Long Henry, Yao Jun, Polyak Kornelia
CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
CANCER RES
2015 ;75 (7) :1516 -1526
-
Ihn Myong Hoon, Kim Young Hoon, Kim Duck-Woo, Oh Heung-Kwon, Lee Soo Young, Park Jin Taek, Son Il Tae, Park Ji Hoon, Lee Yoon Jin, Kim Jin Won, Lee Keun-Wook, Kim Jee Hyun, Shin Eun, Lee Hye Seung, Ahn Soyeon, Kang Sung-Bum
Effects of Preoperative Chemoradiotherapy on the Likelihood of Sphincter Preservation Surgery in Locally Advanced Distal Rectal Cancer: A Longitudinal Study Based on Pelvic Magnetic Resonance Imaging
ANN SURG ONCOL
2015 ;22 (7) :2159 -2167
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Kim Hee-Jun, Im Seock-Ah, Keam Bhumsuk, Ham Hye Seon, Lee Kyung Hun, Kim Tae Yong, Kim Yu Jung, Oh Do-Youn, Kim Jee Hyun, Han Wonshik, Jang In-Jin, Kim Tae-You, Park In Ae, Noh Dong Young
ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy
CANCER SCI
2015 ;106 (1) :86 -93
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Moon Sung Ung, Kang Mi Hyun, Sung Ji Hea, Kim Jin Won, Lee Jeong Ok, Kim Yu Jung, Lee Keun Wook, Bang Soo Mee, Lee Jong Seok, Kim Jee Hyun
Effect of Smad3/4 on chemotherapeutic drug sensitivity in colorectal cancer cells
ONCOL REP
2015 ;33 (1) :185 -192
-
Lee H J, Seo A N, Kim E J, Jang M H, Kim Y J, Kim J H, Kim S-W, Ryu H S, Park I A, Im S-A, Gong G, Jung K H, Kim H J, Park S Y
Prognostic and predictive values of EGFR overexpression and EGFR copy number alteration in HER2-positive breast cancer
BRIT J CANCER
2015 ;112 (1) :103 -111
-
Lee Yun-Gyoo, Bang Soo-Mee, Lee Jeong-Ok, Kim Jin Won, Lee Keun-Wook, Kim Jee Hyun, Song Jung Han, Kim Tae-Hee, Kim Ki Woong, Lee Jong-Seok
Five-Year Follow-up Study of Monoclonal Gammopathy of Undetermined Significance in a Korean Elderly Urban Cohort
CANCER RES TREAT
2015 ;47 (2) :215 -220
-
Jung Hee-Won, Kim Jin Won, Kim Ji-Yeon, Kim Sun-Wook, Yang Hyun Kyung, Lee Joon Woo, Lee Keun-Wook, Kim Duck-Woo, Kang Sung-Bum, Kim Kwang-Il, Kim Cheol-Ho, Kim Jee Hyun
Effect of muscle mass on toxicity and survival in patients with colon cancer undergoing adjuvant chemotherapy
SUPPORT CARE CANCER
2015 ;23 (3) :687 -694
-
Kim Yu Jung, Kim Mi-Jung, Lee Jong Seok, Cho Young-Jae, Park Jong Sun, Kim Jin Won, Chang Hyun, Lee Jeong-Ok, Lee Keun-Wook, Kim Jee Hyun, Yoon Ho Il, Bang Soo-Mee, Lee Jae Ho, Lee Choon-Taek
Who should be admitted to the intensive care unit? The outcome of intensive care unit admission in stage IIIB-IV lung cancer patients
MED ONCOL
2014 ;31 (3)
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Kim Jin Won, Kim Yu Jung, Lee Keun-Wook, Chang Hyun, Lee Jeong-Ok, Kim Kwang-Il, Bang Soo-Mee, Lee Jong Seok, Kim Cheol-Ho, Kim Jee Hyun
The early discontinuation of palliative chemotherapy in older patients with cancer
SUPPORT CARE CANCER
2014 ;22 (3) :773 -781
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Sohn Byeong Seok, Park Seong Joon, Kim Jeong Eun, Kim Kyu-Pyo, Hong Yong Sang, Suh Cheolwon, Kim Yong Sung, Kim Seon Young, Im Seock-Ah, Kim Sun Young, Kim Jee Hyun, Ahn Joong Bae, Park Young Suk, Kim Tae Won
Single-nucleotide polymorphisms in the vascular endothelial growth factor pathway and outcomes of patients treated with first-line cytotoxic chemotherapy combined with bevacizumab for advanced colorectal cancer
ONCOLOGY-BASEL
2014 ;87 (5) :280 -292
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Han Jae Joon, Kim Yu Jung, Kim Jin Won, Chang Hyun, Lee Jeong-Ok, Lee Keun-Wook, Jeong Chang Wook, Kim Jee Hyun, Hong Sung Kyu, Bang Soo-Mee, Byun Seok-Soo, Lee Sang Eun, Lee Jong Seok
Salvage treatment with low-dose weekly paclitaxel in elderly or poor performance status patients with metastatic urothelial carcinoma
TUMORI
2014 ;100 (4) :439 -445
-
Kim Seung Tae, Hong Yong Sang, Lim Ho Yeong, Lee Jeeyun, Kim Tae Won, Kim Kyu-Pyo, Kim Sun Young, Baek Ji Yeon, Kim Jee Hyun, Lee Keun-Wook, Chung Ik-Joo, Cho Sang-Hee, Lee Kyung Hee, Shin Sang Joon, Kang Hye Jin, Shin Dong Bok, Lee Jae Won, Jo Sook Jung, Park Young Suk
S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for the first-line treatment of patients with metastatic colorectal cancer: updated results from a phase 3 trial
BMC CANCER
2014 ;14
-
Lee Jeong-Ok, Lee Ju Hyun, Ahn Soyeon, Kim Jin Won, Chang Hyun, Kim Yu Jung, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Lee Jong Seok
Prevalence and risk factors for iron deficiency anemia in the korean population: results of the fifth KoreaNational Health and Nutrition Examination Survey
J KOREAN MED SCI
2014 ;29 (2) :224 -229
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Kim Yu Jung, Kim Su-Jung, Lee June Koo, Choi Won-Suk, Park Jin Hyun, Kim Hee Jun, Sim Sung Hoon, Lee Keun-Wook, Lee Se-Hoon, Kim Jee Hyun, Kim Dong-Wan, Lee Jong Seok, Bang Yung-Jue, Heo Dae Seog
Prediction of survival in terminally ill cancer patients at the time of terminal cancer diagnosis
J CANCER RES CLIN
2014 ;140 (9) :1567 -1574
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Lee Keun-Wook, Kim Yu Jung, Lee Kyung-Hun, Han Sae-Won, Kim Tae-Yong, Oh Do-Youn, Im Seock-Ah, Kim Tae-You, Bang Yung-Jue, Choi In Sil, Kim Jee Hyun
Phase II trial of gemcitabine plus UFT as salvage treatment in oxaliplatin, irinotecan and fluoropyrimidine-refractory metastatic colorectal cancer
CANCER CHEMOTH PHARM
2014 ;74 (3) :447 -455
-
Sim Sung Hoon, Kang Mi-Hyun, Kim Yu Jung, Lee Keun-Wook, Kim Duck-Woo, Kang Sung-Bum, Eom Keun-Yong, Kim Jae-Sung, Lee Hye Seung, Kim Jee Hyun
P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer
BMC CANCER
2014 ;14
-
Hong Yong Sang, Nam Byung-Ho, Kim Kyu-Pyo, Kim Jeong Eun, Park Seong Joon, Park Young Suk, Park Joon Oh, Kim Sun Young, Kim Tae-You, Kim Jee Hyun, Ahn Joong Bae, Lim Seok-Byung, Yu Chang Sik, Kim Jin Cheon, Yun Seong Hyeon, Kim Jong Hoon, Park Jin-Hong, Park Hee Chul, Jung Kyung Hae, Kim Tae Won
Oxaliplatin, fluorouracil, and leucovorin versus fluorouracil and leucovorin as adjuvant chemotherapy for locally advanced rectal cancer after preoperative chemoradiotherapy (ADORE): an open-label, multicentre, phase 2, randomised controlled trial
LANCET ONCOL
2014 ;15 (11) :1245 -1253
-
Jeong Seung-Yong, Park Ji Won, Nam Byung Ho, Kim Sohee, Kang Sung-Bum, Lim Seok-Byung, Choi Hyo Seong, Kim Duck-Woo, Chang Hee Jin, Kim Dae Yong, Jung Kyung Hae, Kim Tae-You, Kang Gyeong Hoon, Chie Eui Kyu, Kim Sun Young, Sohn Dae Kyung, Kim Dae-Hyun, Kim Jae-Sung, Lee Hye Seung, Kim Jee Hyun, Oh Jae Hwan
Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial
LANCET ONCOL
2014 ;15 (7) :767 -774
-
Oh Heung-Kwon, Kang Sung-Bum, Lee Sung-Min, Lee Soo Young, Ihn Myoung Hun, Kim Duck-Woo, Park Ji Hoon, Kim Young Hoon, Lee Kyung Ho, Kim Jae-Sung, Kim Jin Won, Kim Jee Hyun, Chang Tae-Young, Park Sung-Chan, Sohn Dae Kyung, Oh Jae Hwan, Park Ji Won, Ryoo Seung-Bum, Jeong Seung-Yong, Park Kyu Joo
Neoadjuvant chemoradiotherapy affects the indications for lateral pelvic node dissection in mid/low rectal cancer with clinically suspected lateral node involvement: a multicenter retrospective cohort study
ANN SURG ONCOL
2014 ;21 (7) :2280 -2287
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Kim Yeon Wook, Kim Jin Won, Kim Jee-Hyun, Lee Jungsil, Lee Euijae, Kim Moon Young, Yang Hyun Kyung, Chang Hyun
Metastatic testicular tumor presenting as a scrotal hydrocele: An initial manifestation of pancreatic adenocarcinoma
ONCOL LETT
2014 ;7 (6) :1793 -1795
-
Lee Hyun Jung, Kim Dae Young, Keam Bhumsuk, Lee Jeong Hoon, Han Sae-Won, Oh Do-Youn, Yoon Jung Hwan, Kim Tae-You, Kim Yu Jung, Lee Keun Wook, Kim Jin-Wook, Jeong Sook-Hyang, Lee Jong Seok, Kim Jee Hyun, Im Seock-Ah
Lamivudine prophylaxis for hepatitis B virus carrier patients with breast cancer during adjuvant chemotherapy
BREAST CANCER-TOKYO
2014 ;21 (4) :387 -393
-
Yamamoto Shoji, Wu Zhenhua, Russnes Hege G, Takagi Shinji, Peluffo Guillermo, Vaske Charles, Zhao Xi, Moen Vollan Hans Kristian, Maruyama Reo, Ekram Muhammad B, Sun Hanfei, Kim Jee Hyun, Carver Kristopher, Zucca Mattia, Feng Jianxing, Almendro Vanessa, Bessarabova Marina, Rueda Oscar M, Nikolsky Yuri, Caldas Carlos, Liu X Shirley, Polyak Kornelia
JARID1B is a luminal lineage-driving oncogene in breast cancer
CANCER CELL
2014 ;25 (6) :762 -777
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Park Heae Surng, Jang Min Hye, Kim Eun Joo, Kim Hyun Jeong, Lee Hee Jin, Kim Yu Jung, Kim Jee Hyun, Kang Eunyoung, Kim Sung-Won, Kim In Ah, Park So Yeon
High EGFR gene copy number predicts poor outcome in triple-negative breast cancer
MODERN PATHOL
2014 ;27 (9) :1212 -1222
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Lee Hee Jin, Seo An Na, Kim Eun Joo, Jang Min Hye, Suh Koung Jin, Ryu Han Suk, Kim Yu Jung, Kim Jee Hyun, Im Seock-Ah, Gong Gyungyub, Jung Kyung Hae, Park In Ae, Park So Yeon
HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metastatic breast cancer
AM J CLIN PATHOL
2014 ;142 (6) :755 -766
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Kim Yu Jung, Kim Se Hyun, Kim Jin Won, Lee Jeong-Ok, Kim Jee Hyun, Bang Soo-Mee, Lee Jong Seok, Lee Keun-Wook
Gastric cancer with initial bone metastasis: a distinct group of diseases with poor prognosis
EUR J CANCER
2014 ;50 (16) :2810 -2821
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Kim Sung-Bae, Yoo Changhoon, Ro Jungsil, Im Seock-Ah, Im Young-Hyuck, Kim Jee Hyun, Ahn Jin-Hee, Jung Kyung Hae, Song Hong Suk, Kang Seok Yun, Park Hee Sook, Chung Hyun-Cheol
Combination of docetaxel and TSU-68, an oral antiangiogenic agent, in patients with metastatic breast cancer previously treated with anthracycline: randomized phase II multicenter trial
INVEST NEW DRUG
2014 ;32 (4) :753 -761
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Hong Yong Sang, Kim Tae Won, Lee Sung Sook, Kim Kyu-pyo, Lee Jae-Lyun, Kang Yoon-Koo, Shin Sang Joon, Ahn Joong Bae, Jung Kyung Hae, Im Seock-Ah, Kim Tae-You, Kim Jee Hyun, Park Young Suk
A phase II study of bevacizumab, oxaliplatin, and capecitabine in patients with previously untreated metastatic colorectal cancer: a prospective, multicenter trial of the Korean Cancer Study Group
AM J CLIN ONCOL-CANC
2014 ;37 (1) :19 -23
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Kim Jin Won, Lee Keun-Wook, Chun Eun Ju, Choi Sang Il, Park Do Joong, Kim Hyung-Ho, Bang Soo-Mee, Kim Min Jeong, Lee Ju-Hee, Lee Moon-Soo, Lee Jeong-Ok, Kim Yu Jung, Kim Jee Hyun, Lee Jong Seok
A prospective study on the incidence of postoperative venous thromboembolism in Korean gastric cancer patients: an inquiry into the application of Western guidelines to Asian cancer patients
PLOS ONE
2013 ;8 (4)
-
Lee Kyung-Hun, Kim Tae-You, Chang Hye Jung, Han Sae-Won, Oh Do-Youn, Im Seock-Ah, Bang Yung-Jue, Kim Sun Young, Lee Keun-Wook, Kim Jee Hyun, Hong Yong Sang, Kim Tae Won, Park Young Suk, Kang Won Ki, Shin Sang Joon, Ahn Joong Bae, Kang Gyeong Hoon, Jeong Seung-Yong, Park Kyu Joo, Park Jae-Gahb
Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer
CANCER CHEMOTH PHARM
2013 ;71 (4) :843 -851
-
Park Yeon Hee, Im Young-Hyuck, Jung Kyung Hae, Im Seock-Ah, Sohn Joo Hyuk, Ro Jungsil, Ahn Jin-Hee, Kim Sung-Bae, Nam Byung-Ho, Oh Do Youn, Han Sae-Won, Lee Soohyeon, Park In Hae, Lee Keun Seok, Kim Jee Hyun, Kang Seok Yun, Lee Moon Hee, Park Hee Sook, Ahn Jin Seok
Phase III, multicenter, randomized trial of maintenance chemotherapy versus observation in patients with metastatic breast cancer after achieving disease control with six cycles of gemcitabine plus paclitaxel as first-line chemotherapy: KCSG-BR07-02
J CLIN ONCOL
2013 ;31 (14) :1732 -1739
-
Kang Eun Joo, Im Seock-Ah, Oh Do-Youn, Han Sae-Won, Kim Jin-Soo, Choi In Sil, Kim Jin Won, Kim Yu Jung, Kim Jee Hyun, Kim Tae-You, Lee Jong Seok, Bang Yung-Jue, Lee Keun-Wook
Irinotecan combined with 5-fluorouracil and leucovorin third-line chemotherapy after failure of fluoropyrimidine, platinum, and taxane in gastric cancer: treatment outcomes and a prognostic model to predict survival
GASTRIC CANCER
2013 ;16 (4) :581 -589
-
Kim Ji-Yeon, Kim Yu Jung, Lee Keun-Wook, Lee Jong Seok, Kim Duck-Woo, Kang Sung-Bum, Lee Hye Seung, Jang Na Young, Kim Jae-Sung, Kim Jee Hyun
Practical outcome of adjuvant FOLFOX4 chemotherapy in elderly patients with stage III colon cancer: single-center study in Korea
JPN J CLIN ONCOL
2013 ;43 (2) :132 -138
-
Koo Tae Ryool, Eom Keun Yong, Kang Eun Young, Kim Yu Jung, Kim Sung Won, Kim Jee Hyun, Kim Jae Sung, Kim In Ah
Prognostic value of the nodal ratio and ki-67 expression in breast cancer patients treated with postmastectomy radiotherapy
J BREAST CANCER
2013 ;16 (3) :274 -284
-
Kim Su-Jung, Lee Keun-Wook, Kim Yu Jung, Kim Jee Hyun, Park Do Joong, Kim Hyung-Ho, Lee Jong Seok
Safety, compliance, and predictive parameters for dosage modification in adjuvant S-1 chemotherapy for gastric cancer
CANCER SCI
2013 ;104 (1) :116 -123
-
Seo A N, Lee H J, Kim E J, Kim H J, Jang M H, Lee H E, Kim Y J, Kim J H, Park S Y
Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer
BRIT J CANCER
2013 ;109 (10) :2705 -2713
-
Bang Soo-Mee, Kim Ki Woong, Lee Jeong-Ok, Kim Yu Jung, Lee Keun-Wook, Lim Soo, Kim Jee Hyun, Park Young Joo, Chin Ho Jun, Jang Hak-Chul, Lee Jong Seok
Anemia and activities of daily living in the Korean urban elderly population: results from the Korean Longitudinal Study on Health and Aging (KLoSHA)
ANN HEMATOL
2013 ;92 (1) :59 -65
-
Hong Yong Sang, Kim Tae Won, Jung Kyung Hae, Kim Hwa Jung, Kim Kyu-Pyo, Kim Sun Young, Lee Jae-Lyun, Shim Byoung Yong, Zang Dae Young, Kim Jee Hyun, Ahn Joong Bae, Park Young Suk
Randomized phase II study of capecitabine with or without oxaliplatin as first-line treatment for elderly or fragile patients with metastatic colorectal cancer: a prospective, multicenter trial of the Korean Cancer Study Group CO06-01
AM J CLIN ONCOL-CANC
2013 ;36 (6) :565 -571
-
Hong Yong Sang, Lee Jeeyun, Kim Kyu-pyo, Lee Jae-Lyun, Park Young Suk, Park Joon Oh, Park Se Hoon, Kim Sun Young, Baek Ji Yeon, Kim Jee Hyun, Lee Keun-Wook, Kim Tae-You, Kim Tae Won
Multicenter phase II study of second-line bevacizumab plus doublet combination chemotherapy in patients with metastatic colorectal cancer progressed after upfront bevacizumab plus doublet combination chemotherapy
INVEST NEW DRUG
2013 ;31 (1) :183 -191
-
Kim Sun Young, Shim Eun Kyung, Yeo Hyun Yang, Baek Ji Yeon, Hong Yong Sang, Kim Dae Yong, Kim Tae Won, Kim Jee Hyun, Im Seock-Ah, Jung Kyung Hae, Chang Hee Jin
KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials
INT J RADIAT ONCOL
2013 ;85 (1) :201 -207
-
Kim Ji-Won, Kim Jee Hyun, Im Seock-Ah, Lee Kyung-Hun, Kim Jin-Soo, Kim Tae-Yong, Han Sae-Won, Jeon Yoon Kyung, Oh Do-Youn, Kim Tae-You, Park In Ae
Serum epidermal growth factor is associated with prognosis and hormone receptor status in patients with HER2-positive metastatic breast cancer treated with first-line trastuzumab plus taxane chemotherapy
CANCER CHEMOTH PHARM
2013 ;72 (5) :1023 -1029
-
Kim Ji-Won, Kim Jee Hyun, Im Seock-Ah, Kim Yu Jung, Han Hye-Suk, Kim Jin-Soo, Lee Kyung-Hun, Kim Tae-Yong, Han Sae-Won, Jeon Yoon Kyung, Oh Do-Youn, Kim Tae-You, Park In Ae
HER2/CEP17 ratio and HER2 immunohistochemistry predict clinical outcome after first-line trastuzumab plus taxane chemotherapy in patients with HER2 fluorescence in situ hybridization-positive metastatic breast cancer
CANCER CHEMOTH PHARM
2013 ;72 (1) :109 -115
-
Keam Bhumsuk, Im Seock-Ah, Koh Youngil, Han Sae-Won, Oh Do-Youn, Cho Nariya, Kim Jee Hyun, Han Wonshik, Kang Keon Wook, Moon Woo Kyung, Kim Tae-You, Park In Ae, Noh Dong-Young, Chung June-Key, Bang Yung-Jue
Predictive value of FDG PET/CT for pathologic axillary node involvement after neoadjuvant chemotherapy
BREAST CANCER-TOKYO
2013 ;20 (2) :167 -173
-
신동엽, 이정옥, 김지현
Toxicities and functional consequences of systemic chemotherapy in elderly Korean patients with cancer: A prospective cohort study using Comprehensive Geriatric Assessment
J GYNECOL ONCOL
2012 ;3 (4) :359 -367
-
Koh Youngil, Lee Hee Eun, Oh Do-Youn, Kim Jee Hyun, Lee Se-Hoon, Kim Se Hyung, Kim Dong-Wan, Im Seock-Ah, Kim Tae-You, Heo Dae Seog, Kim Woo-Ho, Bang Yung-Jue
The lack of CD34 expression in gastrointestinal stromal tumors is related to cystic degeneration following imatinib use
JPN J CLIN ONCOL
2012 ;42 (11) :1020 -1027
-
Choi Yoomi, Kim Eun Joo, Seol Hyesil, Lee Hee Eun, Jang Mi Jung, Kim Sun Mi, Kim Jee Hyun, Kim Sung-Won, Choe Gheeyoung, Park So Yeon
The hormone receptor, human epidermal growth factor receptor 2, and molecular subtype status of individual tumor foci in multifocal/multicentric invasive ductal carcinoma of breast
HUM PATHOL
2012 ;43 (1) :48 -55
-
Hong Yong Sang, Park Young Suk, Lim Ho Yeong, Lee Jeeyun, Kim Tae Won, Kim Kyu-pyo, Kim Sun Young, Baek Ji Yeon, Kim Jee Hyun, Lee Keun-Wook, Chung Ik-Joo, Cho Sang-Hee, Lee Kyung Hee, Shin Sang Joon, Kang Hye Jin, Shin Dong Bok, Jo Sook Jung, Lee Jae Won
S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for first-line treatment of patients with metastatic colorectal cancer: a randomised, non-inferiority phase 3 trial
LANCET ONCOL
2012 ;13 (11) :1125 -1132
-
Im Seock-Ah, Ha Sung Whan, Lee Keun Seok, Ro Jungsil, Lee Eun Sook, Kwon Youngmee, Ahn Jin-Hee, Ahn Jin Seok, Kim Jee Hyun, Kang Han Sung, Shin Kyung Hwan, Noh Dong-Young, Park In-Ae, Kim Sung-Bae, Im Young Hyuck
Phase II trial of preoperative paclitaxel, gemcitabine, and trastuzumab combination therapy in HER2 positive stage II/III breast cancer: the Korean Cancer Study Group BR 07-01
BREAST CANCER RES TR
2012 ;132 (2) :589 -600
-
Kim Jae-Sung, Lim Joo Han, Yoon Yong Bum, Kim Jee Hyun, Im Seock-Ah, Chie Eui Kyu, Hwang Jin-Hyeok, Kim Tae-You, Bang Yung-Jue, Ha Sung Whan
Phase II clinical trial of induction chemotherapy with fixed dose rate gemcitabine and cisplatin followed by concurrent chemoradiotherapy with capecitabine for locally advanced pancreatic cancer
CANCER CHEMOTH PHARM
2012 ;70 (3) :381 -389
-
Suh Dong Hoon, Kang Sokbom, Lim Myong Cheol, Lee Taek Sang, Park Jeong-Yeol, Kim Tae-Joong, Kim Jee Hyun, Lee Kwang-Beom, Park Dong Choon, Chung Hyun Hoon, Kim Kidong, Seo Sang-Soo, Kim Hak Jae, Kim Mi-Kyung, Ju Woong, Kim Jae Weon, Lichtman Stuart M, Park Sang-Yoon
Management of the elderly patient with gynecologic cancer: report of the 2011 workshop in geriatric gynecologic oncology
INT J GYNECOL CANCER
2012 ;22 (1) :161 -169
-
Kim N, Park C, Park D J, Kim H-H, Kim S, Kim Y J, Kim J H, Lee J S, Bang Y-J, Khwarg S I, Choung H, Lee M J, Lee K-W
Lacrimal drainage obstruction in gastric cancer patients receiving S-1 chemotherapy
ANN ONCOL
2012 ;23 (8) :2065 -2071
-
Seol Hyesil, Lee Hyun Ju, Choi Yoomi, Lee Hee Eun, Kim Yu Jung, Kim Jee Hyun, Kang Eunyoung, Kim Sung-Won, Park So Yeon
Intratumoral heterogeneity of HER2 gene amplification in breast cancer: its clinicopathological significance
MODERN PATHOL
2012 ;25 (7) :938 -948
-
Kim Mi-Yeong, Kang Sung-Yoon, Lee Suh-Young, Yang Min-Suk, Kim Min-Hye, Song Woo-Jung, Kim Sae-Hoon, Kim You Jung, Lee Keun-Wook, Cho Sang-Heon, Min Kyung-Up, Lee Jong Seok, Kim Jee Hyun, Chang Yoon-Seok
Hypersensitivity reactions to oxaliplatin: clinical features and risk factors in Koreans
ASIAN PAC J CANCER P
2012 ;13 (4) :1209 -1215
-
Park So Yeon, Kwon Hyeong Ju, Choi Yoomi, Lee Hee Eun, Kim Sung-Won, Kim Jee Hyun, Kim In Ah, Jung Namhee, Cho Nam-Yun, Kang Gyeong Hoon
Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes
MODERN PATHOL
2012 ;25 (2) :185 -196
-
Kim Mi-Jung, Lee Hye Seung, Kim Jee Hyun, Kim Yu Jung, Kwon Ji Hyun, Lee Jeong-Ok, Bang Soo-Mee, Park Kyoung Un, Kim Duck-Woo, Kang Sung-Bum, Kim Jae-Sung, Lee Jong Seok, Lee Keun-Wook
Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer
BMC CANCER
2012 ;12
-
Park Jin Hyun, Kim Yu Jung, Lee Jeong-Ok, Lee Keun-Wook, Kim Jee Hyun, Bang Soo-Mee, Chung Jin-Haeng, Kim Jae Sung, Lee Jong Seok
Clinical outcomes of leptomeningeal metastasis in patients with non-small cell lung cancer in the modern chemotherapy era
LUNG CANCER
2012 ;76 (3) :387 -392
-
Kim Hee-Jun, Im Seock-Ah, Keam Bhumsuk, Kim Yu-Jung, Han Sae-Won, Kim Tae Min, Oh Do-Youn, Kim Jee Hyun, Lee Se-Hoon, Chie Eui Kyu, Han Wonshik, Kim Dong-Wan, Kim Tae-You, Noh Dong-Young, Heo Dae Seog, Park In Ae, Bang Yung-Jue, Ha Sung Whan
Clinical outcome of central nervous system metastases from breast cancer: differences in survival depending on systemic treatment
J NEURO-ONCOL
2012 ;106 (2) :303 -313
-
Kim Ji-Won, Kim Jee Hyun, Im Seock-Ah, Kim Yu Jung, Han Hye-Suk, Kim Jin-Soo, Han Sae-Won, Jeon Yoon Kyung, Oh Do-Youn, Han Wonshik, Kim Tae-You, Park In Ae, Noh Dong-Young, Bang Yung-Jue
ABCB1, FCGR2A, and FCGR3A polymorphisms in patients with HER2-positive metastatic breast cancer who were treated with first-line taxane plus trastuzumab chemotherapy
ONCOLOGY-BASEL
2012 ;83 (4) :218 -227
-
김지현, 한태진, 김인아
The prognostic value of the nodal ratio in N1 breast cancer
RADIAT ONCOL
2011 ;6
-
김지현, 고영길, 임석아
VEGF expression is related to good response and long progression-free survival in gastrointestinal stromal tumor patients treated with Sunitinib.
DIAGN MOL PATHOL
2011 ;20 (3) :143 -147
-
김지현, 김욱하, 김재용
Temozolomide for malignant primary spinal cord glioma: an experience of six cases and a literature review.
J NEURO-ONCOL
2011 ;101 (2) :247 -254
-
김지현, 장나영, 김재성
The role of carcinoembryonic antigen after neoadjuvant chemoradiotherapy in patients with rectal cancer.
DIS COLON RECTUM
2011 ;54 (2) :245 -252
-
Metastatic Adrenocortical Carcinoma Presenting Simultaneously with Cushing's and Conn's Syndromes: A Case Report
JPN J CLIN ONCOL
2011 ;41 (11) :1287 -1291
-
김지현, 이근욱, 최세윤
Different characteristics and prognostic impact of deep-vein thrombosis / pulmonary embolism and intraabdominal venous thrombosis in colorectal cancer patients.
THROMB HAEMOSTASIS
2011 ;106 (6) :1084 -1094
-
김지현, 김범석, 임석아
Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis.
BREAST CANCER RES
2011 ;13 (2)
-
김지현, 강현철, 김인아
Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53.
J NEURO-ONCOL
2011 ;102 (1) :157 -162
-
김지현, 이현정, 이근욱
Efficacy and Safety of Hepatic Arterial Infusion of Fluorouracil with Leucovorin as Salvage Treatment for Refractory Liver Metastases from Colorectal Cancer
THE KOREAN JOURNAL OF INTERNAL MEDICINE
2011 ;26 (1) :82 -88
-
김지현, 김재용, 최호용
Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor in the Cerebellopontine Angle : Diagnosis and Treatment Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor in the Cerebellopontine Angle : Diagnosis and Treatment
J KOREAN NEUROSURG S
2011 ;49 (6) :359 -362
-
김지현, 김선영, 정경혜
Preoperative chemoradiation with cetuximab, irinotecan, and capecitabine in patients with locally advanced resectable rectal cancer: a multicenter Phase II study.
INT J RADIAT ONCOL
2011 ;18 (367) :677 -683
-
김지현, 이근욱, 이종석
Two consecutive cases of platinum-refractory pulmonary pleomorphic carcinoma that showed dramatic responses to MAID (mesna, doxorubicin, ifosfamide and dacarbazine) chemotherapy.
JPN J CLIN ONCOL
2011 ;41 (3) :430 -433
-
김지현, 최인실, 이근욱
Biomarker analysis in patients with advanced gastric cancer treated with S-1 plus cisplatin chemotherapy: orotate phosphoribosyltransferase expression is associated with treatment outcomes.
MED ONCOL
2011 ;28 (4) :991 -998
-
김지현, 김일한, 정희원
Radiotherapy followed by adjuvant temozolomide with or without neoadjuvant ACNU-CDDP chemotherapy in newly diagnosed glioblastomas: a prospective randomized controlled multicenter phase III trial.
J NEURO-ONCOL
2011 ;103 (3) :595 -602
-
김지현, 박소연, 강경훈
Promoter CpG island hypermethylation during breast cancer progression.
VIRCHOWS ARCH
2011 ;458 (1) :73 -84
-
김지현, HE Lee, 박소연
An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer
BRIT J CANCER
2011 ;104 (11) :1730 -1738
-
김지현, 방수미, 박현경
Prevalence of monoclonal gammopathy of undetermined significance in an elderly urban Korean population
AM J HEMATOL
2011 ;86 (9) :752 -755
-
김지현, 김기환, 이근욱
Survival benefit of gastrectomy ± metastasectomy in patients with metastatic gastric cancer receiving chemotherapy
GASTRIC CANCER
2011 ;14 (0) :130 -138
-
김지현, 김범석, 임석아
Early metabolic response using FDG PET/CT and molecular phenotypes of breast cancer treated with neoadjuvant chemotherapy
BMC CANCER
2011
-
김지현, 김범석, 임석아
Nomogram predicting clinical outcomes in breast cancer patients treated with neoadjuvant chemotherapy
J CANCER RES CLIN
2011 ;20 :76 -76
-
김지현, 김유정, 방수미
Comprehensive geriatric assessment in Korean elderly cancer patients receiving chemotherapy
J CANCER RES CLIN
2011 ;137 (5) :839 -847
-
Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers
BREAST CANCER RES
2010 ;12 (2)
-
Anaplastic Thyroid Carcinoma Initially Presented with
Abdominal Cutaneous Mass and HyperthyroidismTHE KOREAN JOURNAL OF INTERNAL MEDICINE
2010 ;25 (4) :450 -453
-
Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial
LANCET ONCOL
2010 ;11 (7) :637 -645
-
Real-time contrast-enhanced ultrasound-guided biopsy of focal hepatic lesions not localised on B-mode ultrasound
EUR J RADIOL
2010 ;20 (8) :2047 -2056
-
A multicenter phase II study of gemcitabine and S-1 combination chemotherapy in patients with unresectable pancreatic cancer
CANCER CHEMOTH PHARM
2010 ;65 (3) :527 -536
-
Five-years of Breast Cancer Management in a New Hospital: Analysis Using Clinical Data Warehouse
J BREAST CANC
2010 ;13 :96 -103
-
The Discrepancy Between Genetic Polymorphism of p53 Codon 72 and the Expression of p53 Protein in Helicobacter pylori-Associated Gastric Cancer in Korea
DIGEST DIS SCI
2010 ;55 :101 -110
-
The incidence, risk factors and prognostic implications of venous thromboembolism in patients with gastric cancer
J THROMB HAEMOST
2010 ;8 :540 -547
-
Three-weekly S-1 plus cisplatin chemotherapy as first-line treatment for advanced gastric cancer
MED ONCOL
2010 ;27 (3) :992 -997
-
Severe pulmonary adverse effects in lymphoma patients treated with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) regimen plus rituximab
THE KOREAN JOURNAL OF INTERNAL MEDICINE
2010 ;25 (1) :86 -92
-
Individualized Tumor Response Testing for Prediction of Response to Paclitaxel and Cisplatin Chemotherapy in Patients with Advanced Gastric Cancer
J KOREAN MED SCI
2010 ;25 (5) :684 -690
-
Triple negativity and young age as prognostic factors in lymph node-negative invasive ductal carcinoma of 1 cm or less
BMC CANCER
2010 ;10
-
김지현, 박한기, 장윤석
Doxorubicin에 과민반응을 보인 유방암 환자에서 성공적으로 시행한 Epirubicin 탈감작 요법 1예
천식 및 알레르기
2009 ;29 (2) :127 -131
-
김지현, 이원우, 이효상
대장직장암 간전이 환자에서 수술전 FDG PET의 예후인자로서의 중요성
Nucl Med Mol Imaging
2009 ;43 (5) :429 -435
-
김지현, 김범석, 임석아
Clinical significance of axillary nodal ratio in stage II/III breast cancer treated with neoadjuvant chemotherapy.
BREAST CANCER RES TR
2009 ;116 (0) :153 -160
-
김지현, 이근욱, 허대석
Risk factors for poor treatment outcome and central nervous system relapse in diffuse large B-cell lymphoma with bone marrow involvement.
ANN HEMATOL
2009
-
김지현, 이정옥, 오도연
combination chemotherapy with capecitanine and cisplatin for patients with metastatic hepatocellular carinoma
ANN ONCOL
2009
-
김지현, 김혜진, 이근욱
Chemotherapy-induced transient CEA and CA19-9 surges in patients with metastatic or recurrent gastric cancer
ACTA ONCOL
2009
-
김지현, 한혜숙, 이근욱
Weight changes after adjuvant treatment in Korean women with early breast cancer.
BREAST CANCER RES TR
2009
-
김지현, 이정옥, 이근욱
Metastatic adrenocortical carcinoma treated with sunitinib: a case report.
JPN J CLIN ONCOL
2009
-
김지현, 한혜숙, 임석아
Weekly paclitaxel and trastuzumab as a first-line therapy in patients with HER2-overexpressing metastatic breast cancer: magnitude of HER2/neu amplification as a predictive factor for efficacy.
J KOREAN MED SCI
2009
-
김지현, 선종무, 이종석
Efficacy and Toxicity of Pemetrexed as a Third-line Treatment for Non-small Cell Lung Cancer
JPN J CLIN ONCOL
2009
-
Reduced dose intensity FOLFOX-4 as first line palliative chemotherapy in elderly patients with advanced colorectal cancer
Journal of Korean Medical Science
2005
-
Cytotoxic effects of pemetrexed in gastric cancer cells
Cancer Science
2005
저서 및 특허 ●
| 번호 | 매체명 | 제목 | 발간일 |
|---|---|---|---|
| 112 | 중앙일보 헬스미디어 | “개인 맞춤형 정밀의료가 항암 치료의 표준 될 것”
|
2023-09-18 |
| 111 | 청년의사 | 세계 유방암 치료 트렌드 이끄는 한국 종양내과 전문의들
|
2023-07-24 |
| 110 | 코메디닷컴 | 최초 CDK4/6 표적 유방암약 '입랜스'...폐경 여부 상관없이 사용 가능
|
2023-07-19 |
| 109 | 헬스경향 | "조기유방암환자 한 명에 가족들의 미래 달려"
|
2023-05-09 |
| 108 | 헬스경향 | 조기유방암 재발의 공포, 고위험군 관리만이 유일한 답
|
2023-04-28 |
| 107 | 헬스경향 | "재발위험 높은 조기유방암, 실질적 지원책 고민할 때" | 2023-04-07 |
| 106 | 데일리팜 | 진단부터 치료까지 통합솔루션 제공...기업도 통큰 지원 | 2023-01-19 |
| 105 | 데일리팜 | '최적의 치료를 찾아라'...한국형 정밀의료의 장밋빛 여정 | 2023-01-18 |
| 104 | 청년의사 | 한국 의료진 주도 '유방암 범아시아가이드라인' 등장 | 2022-12-08 |
| 103 | 의사신문 | [병원계 소식] 11월 18일 | 2022-11-18 |
-
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BSI ISO27001
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인증번호 : PHIS 731156
유효기간 : 2023.09.15 ~ 2025.10.30 -
BSI ISO27701
인증번호 : PM 789919
유효기간 : 2023.07.17 ~ 2026.07.16 -
ISMS 인증
인증범위 : 의료정보시스템(OCS,EMR 및 홈페이지 서비스 운영)
유효기간 : 2021.01.06 ~ 2024.01.05
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의료기관 인증
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BSI ISO27001
인증번호 : IS 679936
