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다양하고 유익한 건강상식을 제공해 드립니다.
Seok-Yong Lee, Ho Rim Oh, Young-Hwa Kim, Sung-Hwan Bae, Yongseok Lee, Yun-Sang Lee, Byung Chul Lee, Gi Jeong Cheon, Keon Wook Kang, Hyewon Youn
Cerenkov luminescence imaging of interscapular brown adipose tissue using a TSPO-targeting PET probe in the UCP1 ThermoMouse.
Theranostics
2022 ;12 (14) :6380 -6394
Rosa Maria Iacobazzi, Fabio Vischio, Ilaria Arduino, Fabio Canepa, Valentino Laquintana, Maria Notarnicola, Maria Principia Scavo, Giusy Bianco, Elisabetta Fanizza, Angela Assunta Lopedota, Annalisa Cutrignelli, Antonio Lopalco, Amalia Azzariti, Maria Lucia Curri, Massimo Franco, Gianluigi Giannelli, Byung Chul Lee, Nicoletta Depalo, Nunzio Denora
Magnetic implants in vivo guiding sorafenib liver delivery by superparamagnetic solid lipid nanoparticles.
J Colloid Interface Sci
2022 ;608 (Pt 1) :239 -254
Lawrence K Fung, Ryan E Flores, Meng Gu, Kevin L Sun, David James, Rachel K Schuck, Booil Jo, Jun Hyung Park, Byung Chul Lee, Jae Ho Jung, Sang Eun Kim, Manish Saggar, Matthew D Sacchet, Geoff Warnock, Mohammad Mehdi Khalighi, Daniel Spielman, Frederick T Chin, Antonio Y Hardan
Thalamic and prefrontal GABA concentrations but not GABA<sub>A</sub> receptor densities are altered in high-functioning adults with autism spectrum disorder.
Mol Psychiatry
2021 ;26 (5) :1634 -1646
Sang Hee Lee, Nunzio Denora, Valentino Laquintana, Giuseppe Felice Mangiatordi, Angela Lopedota, Antonio Lopalco, Annalisa Cutrignelli, Massimo Franco, Pietro Delre, In Ho Song, Hye Won Kim, Su Bin Kim, Hyun Soo Park, Kyungmin Kim, Seok-Yong Lee, Hyewon Youn, Byung Chul Lee, Sang Eun Kim
Radiosynthesis and characterization of [18F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism.
Eur J Nucl Med Mol Imaging
2021 ;49 (1) :110 -124
Soyong Lee, Young-Hwa Kim, In Ho Song, Ji Young Choi, Hyewon Youn , Byung Chul Lee, Sang Eun Kim
Evaluation of intracellular uptake of cyclic RGD peptides in integrin αvβ3-expressing tumor cells
Journal of Radiopharmaceuticals and Molecular Probes
2020 ;6 (2) :34 -43
Won Chang Lee, Seok Min Kang, Byung Chul Lee, Sang Eun Kim, Dong Wook Kim
Multifunctional Crown-5-calix[4]arene-based Phase-Transfer Catalysts for Aromatic 18F-Fluorination.
Org Lett
2020 ;22 (24) :9551 -9555
Chiwoo Oh, In Ho Song, Wooseung Lee, Miyeon Jeon, Jinyeong Choi, Seungki Baek, Byung Chul Lee, Sang Eun Kim, Hyung-Jun Im
Brown adipose tissue imaging using the TSPO tracer [18F]fluoromethyl-PBR28-d<sub>2</sub>: A comparison with [18F]FDG.
Nucl Med Biol
2020 ;90-91 :98 -103
Hyun Ho Ah, Byung Seok Moon, Hong Jin Lee, Sang Ju Lee, Seung Jun Lee, Bom Sahn Kim, Byung Chul Lee, Won Woo Lee, Sang Eun Kim, Hyun Sik Park
Comparative Study in Different Filters for Efficient Sterile Filtration
Bulletin of the Korean Chemical Society
2020 ;41 (8) :824 -828
Hyun Soo Park, Yoo Sung Song, Byung Seok Moon, Sung-Eun Yoo, Jae Moon Lee, Yeon-Tae Chung, Eunhee Kim, Byung Chul Lee, Sang Eun Kim
Neurorestorative Effects of a Novel Fas-Associated Factor 1 Inhibitor in the MPTP Model: An [18F]FE-PE2I Positron Emission Tomography Analysis Study.
Front Pharmacol
2020 ;11 :953 -953
Kyungmin Kim, Ha Kim, Sung-Hwan Bae, Seok-Yong Lee, Young-Hwa Kim, Juri Na, Chul-Hee Lee, Min Sun Lee, Guen Bae Ko, Kyeong Yun Kim, Sang-Hee Lee, In Ho Song, Gi Jeong Cheon, Keon Wook Kang, Sang Eun Kim, June-Key Chung, Euishin Edmund Kim, Sun-Ha Paek, Jae Sung Lee, Byung Chul Lee, Hyewon Youn
[18F]CB251 PET/MR imaging probe targeting translocator protein (TSPO) independent of its Polymorphism in a Neuroinflammation Model.
Theranostics
2020 ;10 (20) :9315 -9331
Nam-Young Kang, Jung Yeol Lee, Sang Hee Lee, In Ho Song, Yong Hwa Hwang, Min Jun Kim, Wut Hmone Phue, Bikram Keshari Agrawalla, Si Yan Diana Wan, Janise Lalic, Sung-Jin Park, Jong-Jin Kim, Haw-Young Kwon, So Hee Im, Myung Ae Bae, Jin Hee Ahn, Chang Siang Lim, Adrian Kee Keong Teo, Sunyou Park, Sang Eun Kim, Byung Chul Lee, Dong Yun Lee, Young-Tae Chang
Multimodal Imaging Probe Development for Pancreatic β Cells: From Fluorescence to PET.
J Am Chem Soc
2020 ;142 (7) :3430 -3439
BYUNG CHUL LEE, 장근삼, 김동욱, 이성율, David M. Raffel, 김상은, 공동저자
Control of reactivity and selectivity of guanidinyliodonium salts toward F-18-Labeling by monitoring of protecting groups: Experiment and theory
J FLUORINE CHEM
2019 ;227
Jeong Yoon, Koh Won-Gun, Lee Kangwon, Kim Garam, Jeong Soohyun, Lee Byungchul, Kim Sangeun
Cancer Selective Turn-On Fluorescence Imaging Using a Biopolymeric Nanocarrier
BIOMACROMOLECULES
2019 ;20 (2) :1068 -1076
Denora Nunzio, Lee Byung Chul, Lee Chaedong, Iacobazzi Rosa Maria, Choi Ji Young, Song In Ho, Yoo Jung Sun, Piao Yuanzhe, Lopalco Antonio, Leonetti Francesco, Kim Sang Eun
TSPO-targeted NIR-fluorescent ultra-small iron oxide nanoparticles for glioblastoma imaging
EUR J PHARM SCI
2019 ;139
Das Shyamsundar, Lee Byung Chul, Ko Nakeun, Lee Eunsung, Kim Sang Eun
Stereoselective three-component cascade synthesis of α-substituted 2,4-dienamides from gem-difluorochloro ethanes
Chem. Commun. (Camb.)
2019 ;55 (95) :14355 -14358
Ahn Seong Joon, Woo Se Joon, Lee Byung Chul, Lee Ho-Young, Hong Hye Kyoung, Jung Jae Ho, Park Ji Hyun, Park Kyu Hyung, Kim Sang Eun
Preclinical SPECT Imaging of Choroidal Neovascularization in Mice Using Integrin-Binding 99mTcIDA-D-c(RGDfK)2
MOL IMAGING BIOL
2019 ;21 (4) :644 -653
BYUNG CHUL LEE, 이성식, 장근삼
Origin of Difference in Reactivity of Aliphatic and Aromatic Guanidine-containing Pharmceuticals toward 18Ffluorination: Coulombic Forces and Hydrogen Bonding
B KOREAN CHEM SOC
2019 ;40 :894 -897
BYUNG CHUL LEE, 박현식, 김상은, 공동저자
A simple decontamination procedure for unintended iodide impurity during C-11methionine production
J RADIOANAL NUCL CH
2019 ;322 :933 -939
Hieu Tran Van, Kim Hee-Kwon, Park Hyunjun, Park Jaekyung, Kwon Young-Do, Kang Shinwoo, Ho Jung Jae, Chang Keun-A, Chul Lee Byung, Lee Sang-Yoon, Kang Soosung
Synthesis and evaluation of novel potent TSPO PET ligands with 2-phenylpyrazolo1,5-apyrimidin-3-yl acetamide
BIOORGAN MED CHEM
2019 ;27 (18) :4069 -4080
Lu Yingqing, Choi Ji Young, Kim Sang Eun, Lee Byung Chul
HPLC-free in situ18F-fluoromethylation of bioactive molecules by azidation and MTBD scavenging
Chem. Commun. (Camb.)
2019 ;55 (78) :11798 -11801
Park So Hyeon, Park Hyun Soo, Song Yoo Sung, Moon Byung Seok, Lee Byung Chul, Kim Sang Eun
Combination of In Vivo 123IFP-CIT SPECT and Microdialysis Reveals an Antipsychotic Drug Haloperidol-induced Synaptic Dopamine Availability in the Rat Midbrain and Striatum
EXP NEUROBIOL
2019 ;28 (5) :602 -611
BYUNG CHUL LEE, 최지영, 송인호, 문병석, 김상은, 정재호
Synthesis and biological evaluation of tricarbonyl technetium labeled 2-(4-chloro)phenyl-imidazo1,2-apyridine analog (99mTc-CB257) as a TSPO-binding ligand
J Radiopharm Mol Probes
2018 ;4 (4) :73 -79
Kwon Young-Do, Kang Shinwoo, Park Hyunjun, Cheong Il-Koo, Chang Keun-A, Lee Sang-Yoon, Jung Jae Ho, Lee Byung Chul, Lim Seok Tae, Kim Hee-Kwon
Novel potential pyrazolopyrimidine based translocator protein ligands for the evaluation of neuroinflammation with PET
EUR J MED CHEM
2018 ;159 :292 -306
Lim Soobin, Song Dalnim, Jeon Seungwon, Lee Eunsung, Cho Hyungdo, Kim Youngsuk, Kim Hyunseok, Lee Sanghee, Lee Byung Chul, Kim Sang Eun, Kim Kimoon
Cobalt-Catalyzed C-F Bond Borylation of Aryl Fluorides
ORG LETT
2018 ;20 (22) :7249 -7252
Moon Byung Seok, Jung Jae Ho, Park Hyun Soo, Contino Marialessandra, Denora Nunzio, Lee Byung Chul, Kim Sang Eun
Preclinical comparison study between 18Ffluoromethyl-PBR28 and its deuterated analog in a rat model of neuroinflammation
BIOORG MED CHEM LETT
2018 ;28 (17) :2925 -2929
Song Yoo Sung, Lee Byung Chul, Jung Jae Ho, Park Hyun Soo, Kim Sang Eun, Kim Joong Hyun
Biodistribution and Internal Radiation Dosimetry of 99mTc-IDA-D-c(RGDfK)2 (BIK-505), a Novel SPECT Radiotracer for the Imaging of Integrin αvβ3 Expression
CANCER BIOTHER RADIO
2018 ;33 (9) :396 -402
Kim Ga Ram, Paeng Jin Chul, Jung Jae Ho, Moon Byung Seok, Lopalco Antonio, Denora Nunzio, Lee Byung Chul, Kim Sang Eun
Assessment of TSPO in a Rat Experimental Autoimmune Myocarditis Model: A Comparison Study between 18FFluoromethyl-PBR28 and 18FCB251
INT J MOL SCI
2018 ;19 (1)
Woo Sang-Keun, Moon Byung Seok, Kim Bom Sahn, Kim Min Hwan, Lee Yong Jin, Jung Jae Ho, Lee Kyo Chul, Seo Youngho, Kim Wook, Lim Sang Moo, Lee Byung Chul, Kim Sang Eun
Feasibility of myocardial PET imaging using a benzylguanidine analog: meta-(3-18Ffluoropropyl)benzylguanidine (18FmFPBG)
NUCL MED BIOL
2018 ;61 :63 -70
Fully automated radiosynthesis of 68Gaedotreotide(68GaDOTA-TOC) and its quality controls
Journal of Radiopharmaceuticals and Molecular Prob
2017 ;3 (2) :85 -90
The position of fluorine in CP-118,954 affects AChE inhibition potency and PET imaging quantification for AChE expression in the rat brain
EUR J PHARM SCI
2017 ;109 :209 -216
A Potential PET Radiotracer for the 5-HT2C Receptor: Synthesis and in Vivo Evaluation of 4-(3-18Ffluorophenethoxy)pyrimidine
ACS CHEM NEUROSCI
2017 ;8 (5) :996 -1003
Imaging of Integrin αvβ3 Expression in Lung Cancers and Brain Tumors Using Single-Photon Emission Computed Tomography with a Novel Radiotracer 99mTc-IDA-D-c(RGDfK)2
CANCER BIOTHER RADIO
2017 ;32 (8) :288 -296
Immuno-PET imaging based radioimmunotherapy in head and neck squamous cell carcinoma model
Oncotarget
2017 ;8 (54) :92090 -92105
PET measurement of GABA shift in the rat brain: A preclinical application of bolus plus constant infusion paradigm of (18)Fflumazenil
NUCL MED BIOL
2017 ;45 :30 -34
Recent advances in carbon-11 chemistry
Journal of Radiopharmaceuticals and Molecular Prob
2016 ;2 (1) :7 -14
Consecutive automated production of carbon-11 labeled radiopharmaceuticals by sharing 11C-methylation reagent from one 11C-synthetic module
Journal of Radiopharmaceuticals and Molecular Prob
2016 ;2 (2) :123 -131
Synthesis and in vivo evaluation of a kit-type 99mTc-labeled N-(2-aminoethyl)-3-(4-(2-hydroxy-3-(isopropylaminopropoxy)phenyl)propanamide as a selectiv beta1-adrenoceptor-binding SPECT radiotracer
Bulletin of the Korean Chemical Society
2016 ;37 :2029 -2035
Effects of common anesthetic agents on (18)Fflumazenil binding to the GABAA receptor
EJNMMI RES
2016 ;6 (1)
Design and synthesis of phenoxypyridyl acetamide or aryl-oxodihydropurine derivatives for the development of novel PET imaging targeting the translocator protein 18 kDa (TSPO)
Bulletin of the Korean Chemical Society
2016 ;37 :1874 -1877
Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo1,2-apyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich Cancer
INT J MOL SCI
2016 ;17 (7)
Identification of Angiogenesis Rich-Viable Myocardium using RGD Dimer based SPECT after Myocardial Infarction
SCI REP-UK
2016 ;6
Development of drugs and thechnology for radiation theragnosis
NUCL ENG TECHNOL
2016 ;48 (3) :597 -607
Immuno-PET Imaging and Radioimmunotherapy of 64Cu-/177Lu-Labeled Anti-EGFR Antibody in Esophageal Squamous Cell Carcinoma Model
J NUCL MED
2016 ;57 (7) :1105 -1111
A Novel PET Imaging Probe for the Detection and Monitoring of Translocator Protein 18?kDa Expression in Pathological Disorders
SCI REP-UK
2016 ;6
PET imaging of dopamine transporters with (18)FFE-PE2I: Effects of anti-Parkinsonian drugs
NUCL MED BIOL
2016 ;43 (2) :158 -164
Neuropsychological, Metabolic, and GABAA Receptor Studies in Subjects with Repetitive Traumatic Brain Injury
J NEUROTRAUM
2016 ;33 (11) :1005 -1014
Click Reaction: An Applicable Radiolabeling Method for Molecular Imaging
Nucl Med Mol Imaging
2015
Recent advances of aromatic C-F bond borylation and its application to positron emission tomography
Journal of Radiopharmaceuticals and Molecular Prob
2015
Improvement, operation and management status of the KOTRON-13 cyclotron
Journal of Radiopharmaceuticals and Molecular Prob
2015
Development of additive CO2 target system in the KOTRON-13 cyclotron and its application for radiopharmaceutical production
Nuclear Instruments and Methods in Physics Researc
2015 :356 -357
In Vivo Tissue Pharmacokinetics of Carbon-11-Labeled Clozapine in Healthy Volunteers: A Positron Emission Tomography Study
CPT Pharmacometrics Syst Pharmacol
2015 ;4 (5) :305 -311
SPECT/CT Imaging of High-Risk Atherosclerotic Plaques using Integrin-Binding RGD Dimer Peptides
SCI REP-UK
2015 ;5
(18)FFluoromethyl-PBR28 as a potential radiotracer for TSPO: preclinical comparison with (11)CPBR28 in a rat model of neuroinflammation
BIOCONJUGATE CHEM
2014 ;25 (2) :442 -450
Proof of mechanism study of a novel serotonin transporter blocker, DA-8031, using 11CDASB positron emission tomography and in vivo microdialysis
UROLOGY
2014 ;84 (1) :245.e1 -245.e7
Routine production of (18)fflumazenil from iodonium tosylate using a sample pretreatment method: a 2.5-year production report
MOL IMAGING BIOL
2014 ;16 (5) :619 -625
Synthesis and In vivo Evaluation of 5-Methoxy-2-(phenylethynyl)quinoline (MPEQ) and 11CMPEQ Targeting Metabotropic Glutamate Receptor 5 (mGluR5)
B KOREAN CHEM SOC
2014 ;35 (8) :2304 -2310
Case report of PET/CT imaging of a patient with neuroblastoma using 18F-FPBG
PEDIATRICS
2014 ;134 (6) :e1731 -e1734
BYUNG CHUL LEE
Facile aromatic radiofluorination of (18)Fflumazenil from diaryliodonium salts with evaluation of their stability and selectivity
ORG BIOMOL CHEM
2011 ;9 (24) :8346 -8355
Aromatic radiofluorination and biological evaluation of 2-aryl-6-[F-18] fluorobenzothiazoles as a potential positron emission tomography imaging probe for beta-amyloid plaques .
BIOORGANIC & MEDICINAL CHEMISTRY
2011 ;19 (9) :2980 -2990
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